ReviewClinical & experimental metastasis2007
New concepts in breast cancer metastasis: tumor initiating cells and the microenvironment.
Review in Clinical & experimental metastasis, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Inactivation of EMILIN-1 by Proteolysis and Secretion in Small Extracellular Vesicles Favors Melanoma Progression and Metastasis.International journal of molecular sciences · 2021Article
- Synergistic Roles of Curcumin in Sensitising the Cisplatin Effect on a Cancer Stem Cell-Like Population Derived from Non-Small Cell Lung Cancer Cell Lines.Molecules (Basel, Switzerland) · 2021Article
- CD133 expressionand clinicopathologic significance in benign and malignant breast lesions.Cancer biomarkers : section A of Disease markers · 2020Article
- FNDC3B circular RNA promotes the migration and invasion of gastric cancer cells via the regulation of E-cadherin and CD44 expression.Journal of cellular physiology · 2019Article
- COX-2 induces oncogenic micro RNA miR655 in human breast cancer.Scientific reports · 2018Article
- CD24 Is Not Required for Tumor Initiation and Growth in Murine Breast and Prostate Cancer Models.PloS one · 2016Article
- Lymphadenectomy promotes tumor growth and cancer cell dissemination in the spontaneous RET mouse model of human uveal melanoma.Oncotarget · 2015Article
- Pre-metastatic conditioning of organ microenvironments by tumors: beyond preparing the soil.Journal of molecular medicine (Berlin, Germany) · 2015Article
- Differential remodeling of extracellular matrices by breast cancer initiating cells.Journal of biophotonics · 2015Article
- Vascular remodeling in cancer.Oncogene · 2014Review
- The metastatic niche and stromal progression.Cancer metastasis reviews · 2012Review
- CD24 interacts with and promotes the activity of c-src within lipid rafts in breast cancer cells, thereby increasing integrin-dependent adhesion.Cellular and molecular life sciences : CMLS · 2012Article
- Article
- Preparation of epithelial and mesenchymal stem cells from murine mammary gland.Current protocols in toxicology · 2011Article
- Breast cancer metastatic to the rectum: a case report.Techniques in coloproctology · 2011Article
- Isolation and comparison of mesenchymal stem-like cells from human gastric cancer and adjacent non-cancerous tissues.Journal of cancer research and clinical oncology · 2011Article
- Study of Estrogen Receptor and Progesterone Receptor Expression in Breast Ductal Carcinoma In Situ by Immunohistochemical Staining in ER/PgR-Negative Invasive Breast Cancer.ISRN oncology · 2011Article
- Cancer metastasis as a therapeutic target.European journal of cancer (Oxford, England : 1990) · 2010Review
- Hyaluronan-CD44 Interactions in Cancer: Paradoxes and Possibilities.Clinical cancer research : an official journal of the American Association for Cancer Research · 2009Article
- Caveolin-1 (P132L), a common breast cancer mutation, confers mammary cell invasiveness and defines a novel stem cell/metastasis-associated gene signature.The American journal of pathology · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The currently prevailing ideas that set out to explain the process of metastasis are largely based on observations made on the total tumor cell population, and often focus on tumor-intrinsic properties. The clinical observation that particular tumor types show a predilection to metastasize to particular organs has been understood in terms of Paget's "Seed and Soil" hypothesis, but a definition of the molecular basis for the "Seed and Soil" hypothesis is at best only partial. Recent ideas about the cellular basis of tumor growth (cancer stem cells) and the remote establishment by primary tumors of special permissive microenvironments in target organs prior to metastasis (pre-metastatic niches) have the potential to radically change our view of the metastatic process. In this review we examine these new concepts with a particular emphasis on findings made in the context of breast cancer, and compare these concepts with ideas based on studies using the total tumor cell population.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.