ArticleLangenbeck's archives of surgery2008
Procalcitonin in preoperative diagnosis of abdominal sepsis.
Article in Langenbeck's archives of surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic value of neutrophil CD64, procalcitonin, and interleukin-6 in sepsis: a meta-analysis.BMC infectious diseases · 2021Pooled it
- The Acute Abdomen: Structured Diagnosis and Treatment.Deutsches Arzteblatt international · 2025Review
- The Role of Biomarkers and Scores in Describing Urosepsis.Medicina (Kaunas, Lithuania) · 2023Article
- A study of C-reactive protein and D-dimer in patients of appendicitis.Journal of family medicine and primary care · 2020Article
- Article
- Secondary peritonitis: principles of diagnosis and intervention.BMJ (Clinical research ed.) · 2018Review
- [Characteristics of postoperative peritonitis].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016Review
- Biomarkers for diagnosis of sepsis in patients with systemic inflammatory response syndrome: a systematic review and meta-analysis.SpringerPlus · 2016Article
- Predictive values for procalcitonin in the diagnosis of neonatal sepsis.Electronic physician · 2015Article
- Procalcitonin as an early diagnostic and monitoring tool in urosepsis following percutaneous nephrolithotomy.Urolithiasis · 2015Article
- Prediction of mortality in patients with colorectal perforation based on routinely available parameters: a retrospective study.World journal of emergency surgery : WJES · 2015Article
- The value of C-reactive protein and lactate in the acute abdomen in the emergency department.World journal of emergency surgery : WJES · 2012Article
- PCR-based rapid sepsis diagnosis effectively guides clinical treatment in patients with new onset of SIRS.Langenbeck's archives of surgery · 2012Article
- The diagnostic value of D-dimer, procalcitonin and CRP in acute appendicitis.International journal of medical sciences · 2012Article
- [Procalcitonin-based algorithm. Management of antibiotic therapy in critically ill patients].Der Anaesthesist · 2011Review
- The rapidly expanding role of procalcitonin as a diagnostic and prognostic assay besides in UTIs.International urology and nephrology · 2009Article
- Treatment of the open abdomen with the commercially available vacuum-assisted closure system in patients with abdominal sepsis: low primary closure rate.World journal of surgery · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThe present study attempted to identify the diagnostic significance of procalcitonin (PCT) in acute abdominal conditions as well as the range of concentrations relating to diagnosis of abdominal sepsis. MATERIALS AND
methodsThis was prospective clinical study. The study included 98 consecutive patients with acute abdominal conditions, divided in sepsis and systemic inflammatory response syndrome (SIRS) group.
resultsPCT concentrations on admission were significantly higher in the sepsis group than in the SIRS group (median [interquartile range] 2.32 [7.41] vs 0.45 ng/ml [2.62]). A cutoff value of 1.1 ng/ml yielded 72.4% sensitivity and 62.5% specificity. In a group of patients with abdominal symptoms lasting for more than 24 h, a cut-off value of 1.1 ng/ml yielded higher sensitivity (82.9%) and higher specificity (77.3%).
conclusionOur results suggest that PCT measurements may be useful for early, preoperative diagnosis of abdominal sepsis.
Indexed as
Identifiers
17968584What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.