ReviewPediatric surgery international2007
Interstitial cells of Cajal in the normal gut and in intestinal motility disorders of childhood.
Review in Pediatric surgery international, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Megacystis microcolon intestinal hypoperistalsis syndrome: systematic review of outcome.Pediatric surgery international · 2011Pooled it
- Interstitial cells of Cajal: clinical relevance in pediatric gastrointestinal motility disorders.Pediatric surgery international · 2023Review
- Challenges in the diagnosis of intestinal neuronal dysplasia type B: A look beyond the number of ganglion cells.World journal of gastroenterology · 2021Review
- Activated M1 macrophages suppress c-kit expression via TNF-α-mediated upregulation of miR-222 in Neonatal Necrotizing Enterocolitis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021Article
- Intestinal hypomotility in systemic sclerosis: a histological study into the sequence of events.Clinical rheumatology · 2021Article
- The role of HCN channels in peristaltic dysfunction in human ureteral tuberculosis.International urology and nephrology · 2018Article
- Pathological changes of interstitial cells of Cajal and ganglion cells in the segment of resected bowel in Hirschsprung's disease.Pediatric surgery international · 2016Article
- Chagasic megacolon: enteric neurons and related structures.Histochemistry and cell biology · 2014Review
- Heterozygous de novo and inherited mutations in the smooth muscle actin (ACTG2) gene underlie megacystis-microcolon-intestinal hypoperistalsis syndrome.PLoS genetics · 2014Article
- Article
- Interstitial cells of Cajal in the normal human gut and in Hirschsprung disease.Pediatric surgery international · 2013Review
- Classification and diagnostic criteria of variants of Hirschsprung's disease.Pediatric surgery international · 2013Review
- Disruption of interstitial cells of Cajal networks after massive small bowel resection.World journal of gastroenterology · 2013Article
- Application of three-dimensional imaging to the intestinal crypt organoids and biopsied intestinal tissues.TheScientificWorldJournal · 2013Article
- Involvement of interstitial cells of Cajal in experimental severe acute pancreatitis in rats.World journal of gastroenterology · 2013Article
- Cells derived from the coelomic epithelium contribute to multiple gastrointestinal tissues in mouse embryos.PloS one · 2013Article
- Interstitial cells of Cajal, the Maestro in health and disease.World journal of gastroenterology · 2010Review
- ICC-MY coordinate smooth muscle electrical and mechanical activity in the murine small intestine.Neurogastroenterology and motility · 2010Article
- Influence of Interstitial Cells of Cajal in Congenital Ureteropelvic Junction Obstruction.Journal of Indian Association of Pediatric SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interstitial cells of Cajal (ICCs) are pacemaker cells which are densely distributed throughout the whole gastrointestinal tract. ICCs have important functions in neurotransmission, generation of slow waves and regulation of mechanical activities in the gastrointestinal tract, especially for the coordinated gastrointestinal peristalsis. Therefore, a loss of ICCs could result in gastrointestinal motor dysfunction. In recent years c-kit labeling has been widely used to study pathological changes of ICCs in gastrointestinal motility disorders. Paediatric gastrointestinal motility disorders such as hypertrophic pyloric stenosis, Hirschsprung's disease, total colonic aganglionosis, hypoganglionosis, intestinal neuronal dysplasia, internal anal sphincter achalasia, megacystis microcolon intestinal hypoperistalsis syndrome have been reported to be associated with loss or deficiency of ICCs networks. This review describes the distribution of ICCs in the normal gastrointestinal tract and its altered distribution in intestinal motility disorders of childhood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.