Evidence map›Paper›PMID 17967435›Full record

ReviewCurrent opinion in chemical biology2007

Model systems for understanding DNA base pairing.

Andrew T Krueger, Eric T Kool

Abstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
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  9. Article
  10. Artificial genetic sets composed of size-expanded base pairs.Angewandte Chemie (International ed. in English) · 2013
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Encoding phenotype in bacteria with an alternative genetic set.Journal of the American Chemical Society · 2011
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew T KruegerDepartment of Chemistry, Stanford University, Stanford, CA 94305-5080, USA.
Eric T Kool

Funding

Probing Nucleotide Recognition in the Genetic Information PathwayR01GM072705 · NIGMS · STANFORD UNIVERSITY · PI KOOL, ERIC T. · 2004 to 2012
$2.4M
RE-ENGINEERING THE DIAMETER OF THE DOULBE HELIXR01GM063587 · NIGMS · STANFORD UNIVERSITY · PI KOOL, ERIC T. · 2001 to 2010
$2.2M
NIGMS NIH HHS GM072705NIGMS NIH HHS GM63587NIGMS NIH HHS R01 GM063587NIGMS NIH HHS R01 GM072705
6 · The paper itself

Abstract

The fact that nucleic acid bases recognize each other to form pairs is a canonical part of the dogma of biology. However, they do not recognize each other well enough in water to account for the selectivity and efficiency that is needed in the transmission of biological information through a cell. Thus proteins assist in this recognition in multiple ways, and recent data suggest that these mechanisms of recognition can vary widely with context. To probe how the chemical differences of the four nucleobases are defined in various biological contexts, chemists and biochemists have developed modified versions that differ in their polarity, shape, size, and functional groups. This brief review covers recent advances in this field of research.

Indexed as

Base PairingModels, BiologicalModels, ChemicalDNAHydrogen BondingStatic ElectricityDNA

Identifiers

PMID17967435
PMCPMC2175026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.