Evidence map›Paper›PMID 17967406›Full record

ReviewImmunity2007

Targeting V(D)J recombinase: putting a PHD to work.

Eugene M Oltz, Oleg Osipovich

Open access · bronzeAbstract readCommentReview
PubMed Publisher
In one paragraph

Review in Immunity, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The evolution of multiple isotypic IgM heavy chain genes in the shark.Journal of immunology (Baltimore, Md. : 1950) · 2008
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eugene M OltzDepartment of Microbiology and Immunology, Vanderbilt University Medical School, Nashville, TN 37232, USA. eugene.oltz@vanderbilt.edu
Oleg Osipovich
Vanderbilt University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Immunity, Liu et al. (2007) show that V(D)J recombinase binds chromatin marked by H3K4 trimethylation. Because this mark associates with active promoters, the finding forges a new link between transcription, epigenetics, and recombinase targeting during lymphocyte development.

Indexed as

Genes, ImmunoglobulinModels, GeneticTranscription, GeneticAnimalsEpigenesis, GeneticGene Rearrangement, T-LymphocyteHumansLymphocytesModels, ImmunologicalVDJ RecombinasesVDJ Recombinases

Identifiers

PMID17967406
OpenAlexW2028731219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.