ArticleCellular & molecular biology letters2008
The transcription reinitiation properties of RNA polymerase III in the absence of transcription factors.
Article in Cellular & molecular biology letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Human RNase P exhibits and controls distinct ribonucleolytic activities required for ordered maturation of tRNA.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Human RNase P ribonucleoprotein is required for formation of initiation complexes of RNA polymerase III.Nucleic acids research · 2015Article
- Investigating transcription reinitiation through in vitro approaches.Transcription · 2014Review
- Genome-wide location analysis reveals a role for Sub1 in RNA polymerase III transcription.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Facilitated recycling protects human RNA polymerase III from repression by Maf1 in vitro.The Journal of biological chemistry · 2008Article
- Function and assembly of a chromatin-associated RNase P that is required for efficient transcription by RNA polymerase I.PloS one · 2008Article
- Transcription termination by the eukaryotic RNA polymerase III.Biochimica et biophysica actaReview
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
Transcription reinitiation by RNA polymerase (Pol) III proceeds through facilitated recycling, a process by which the terminating Pol III, assisted by the transcription factors TFIIIB and TFIIIC, rapidly reloads onto the same transcription unit. To get further insight into the Pol III transcription mechanism, we analyzed the kinetics of transcription initiation and reinitiation of a simplified in vitro transcription system consisting only of Pol III and template DNA. The data indicates that, in the absence of transcription factors, first-round transcription initiation by Pol III proceeds at a normal rate, while facilitated reinitiation during subsequent cycles is compromised.
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