Evidence map›Paper›PMID 17965208›Full record

ArticleApplied and environmental microbiology2007

Molecular dissection of a bifidobacterial replicon.

Michelle Cronin, Moritz Knobel, Mary O'Connell-Motherway, Gerald F Fitzgerald, Douwe van Sinderen

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Discovery of a conjugative megaplasmid in Bifidobacterium breve.Applied and environmental microbiology · 2015
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Accessing the inaccessible: molecular tools for bifidobacteria.Applied and environmental microbiology · 2012
    Review
  13. Article
  14. Article
  15. Genomic insights into bifidobacteria.Microbiology and molecular biology reviews : MMBR · 2010
    Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michelle CroninDepartment of Microbiology, National University of Ireland, Western Road, Cork, Ireland.
Moritz Knobel
Mary O'Connell-Motherway
Gerald F Fitzgerald
Douwe van Sinderen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2.1-kb cryptic plasmid pCIBAO89 from Bifidobacterium asteroides harbors a 1.4-kb segment which is sufficient for its autonomous replication. The segment is divided into two parts, the presumed replication origin, ori89, and the rep gene encoding the putative 41-kDa Rep89 replication initiation protein. This minimal replication region of pCIBAO89 was functionally dissected by transcriptional analyses as well as by DNA-binding studies, and the information obtained was exploited to create a number of Escherichia coli-Bifidobacterium shuttle vectors capable of transforming various bifidobacteria with an efficiency of up to 10(6) transformants/mug DNA.

Indexed as

BifidobacteriumDNA, BacterialDNA-Binding ProteinsDNA HelicasesEscherichia coliGenetic VectorsMolecular Sequence DataPlasmidsProtein BindingReplication OriginRepliconSequence Analysis, DNATrans-ActivatorsTranscription, GeneticTransformation, BacterialDNA, BacterialDNA-Binding ProteinsDNA Helicasesreplication initiator proteinTrans-Activators

Identifiers

PMID17965208
PMCPMC2168138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.