ArticleBiophysical journal2008
Fast fluorescence laser tracking microrheometry. I: instrument development.
Article in Biophysical journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Saponins of Dioscorea Nipponicae Inhibits IL-17A-Induced Changes in Biomechanical Behaviors of In Vitro Cultured Human Airway Smooth Muscle Cells.Journal of engineering and science in medical diagnostics and therapy · 2019Article
- Optical Thromboelastography to evaluate whole blood coagulation.Journal of biophotonics · 2015Article
- Hyperglycemic and hyperlipidemic conditions alter cardiac cell biomechanical properties.Biophysical journal · 2014Article
- Correction of optical absorption and scattering variations in Laser Speckle Rheology measurements.Optics express · 2014Article
- Optical measurement of arterial mechanical properties: from atherosclerotic plaque initiation to rupture.Journal of biomedical optics · 2013Review
- Evaluation and correction for optical scattering variations in laser speckle rheology of biological fluids.PloS one · 2013Article
- Mechanobiology in lung epithelial cells: measurements, perturbations, and responses.Comprehensive Physiology · 2012Review
- Characterization of hydrogel microstructure using laser tweezers particle tracking and confocal reflection imaging.Journal of physics. Condensed matter : an Institute of Physics journal · 2010Article
- A general method for improving spatial resolution by optimization of electron multiplication in CCD imaging.Optics express · 2010Article
- Fast fluorescence laser tracking microrheometry, II: quantitative studies of cytoskeletal mechanotransduction.Biophysical journal · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
To gain insight into cellular mechanotransduction pathways, we have developed a fluorescence laser tracking microrheometer (FLTM) to measure material rheological features on micrometer length scales using fluorescent microspheres as tracer particles. The statistical analysis of the Brownian motion of a particle quantifies the viscoelastic properties of the probe's environment, parameterized by the frequency-dependent complex shear modulus G*(omega). This FLTM has nanometer spatial resolution over a frequency range extending from 1 Hz to 50 kHz. In this work, we first describe the consecutive stages of instrument design, development, and optimization. We subsequently demonstrate the accuracy of the FLTM by reproducing satisfactorily the known rheological characteristics of purely viscous glycerol solutions and cross-linked polyacrylamide polymer networks. An upcoming companion article will illustrate the use of FLTM in studying the solid-like versus liquid-like rheological properties of fibroblast cytoskeletons in living biological samples.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.