Evidence map›Paper›PMID 17964287›Full record

ArticleBiochemical and biophysical research communications2007

Identification of putative Arabidopsis DEMETER target genes by GeneChip analysis.

Hyonhwa Ohr, Anhthu Q Bui, Brandon H Le, Robert L Fischer, Yeonhee Choi

Open access · greenAbstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Base Excision DNA Repair in Plants:International journal of molecular sciences · 2023
    Review
  2. Article
  3. Review
  4. Article
  5. A decade of pollen transcriptomics.Plant reproduction · 2015
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Hyonhwa OhrDepartment of Biological Sciences, Seoul National University, Seoul 151-742, Republic of Korea.
Anhthu Q Bui
Brandon H Le
Robert L Fischer
Yeonhee Choi
Seoul National University · KRUniversity of California, Los Angeles · USUniversity of California, Berkeley · US

Funding

Regulation and Function of DNA Demethylation in ArabidopsisR01GM069415 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI FISCHER, ROBERT L, ZILBERMAN, DANIEL · 2004 to 2016
$3.8M
NIGMS NIH HHS GM069415NIGMS NIH HHS R01 GM069415
6 · The paper itself

Abstract

The Arabidopsis DEMETER (DME) DNA glycosylase is required for the maternal allele expression of imprinted Polycomb group (MEDEA and FIS2) and transcription factor (FWA) genes in the endosperm. Expression of DME in the central cell, not in pollen or stamen, establishes gene imprinting by hypomethylating maternal alleles. However, little is known about other genes regulated by DME. To identify putative DME target genes, we generated CaMV:DME plants which ectopically express DME in pollen and stamens. Comparison of mRNA profiles revealed 94 genes induced by ectopic DME expression in both stamen and pollen. Gene ontology analysis identified three molecular functions enriched in the DME-inducible RNA list: DNA or RNA binding, kinase activity, and transcription factor activity. Semi-quantitative RT-PCR verified the candidate genes identified by GeneChip analysis. The putative target genes identified in this study will provide insights into the regulatory mechanism of DME DNA glycosylase and the functions of DNA demethylation.

Indexed as

ArabidopsisArabidopsis ProteinsBase SequenceChromosome MappingGene TargetingMolecular Sequence DataN-Glycosyl HydrolasesOligonucleotide Array Sequence AnalysisTrans-ActivatorsArabidopsis ProteinsDEMETER protein, ArabidopsisN-Glycosyl HydrolasesTrans-Activators

Identifiers

PMID17964287
PMCPMC2137929
OpenAlexW2008704599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.