ArticleCurrent biology : CB2007
Arabidopsis TANGLED identifies the division plane throughout mitosis and cytokinesis.
Article in Current biology : CB, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
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Who cites it
77 citing papers in PubMed.
- The evolutionary origins of streptophyte multicellularity.The New phytologist · 2026Review
- KATANIN is required for the formation of complete preprophase bands and subsequent division positioning in two asymmetric divisions of the maize stomatal complex.Journal of cell science · 2026Article
- In Vitro Live Cell Imaging Reveals Nuclear Dynamics and Role of the Cytoskeleton During Asymmetric Division of Pollen Mitosis I in Nicotiana Benthamiana.Cytoskeleton (Hoboken, N.J.) · 2026Article
- TON1 and FASS are required to recruit myosin VIII, a cell division guidance factor.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Cellular dynamics and molecular signaling networks of plant cytokinesis.Molecules and cells · 2026Review
- The tail domain of the plant kinesin-12 POK2 is a versatile interaction hub.Journal of cell science · 2025Article
- Kinesin-12 POK2 polarization is a prerequisite for a fully functional division site and aids cell plate positioning.Nature communications · 2025Article
- De novo TANGLED1 recruitment from the phragmoplast to aberrant cell plate fusion sites in maize.Journal of cell science · 2024Article
- Article
- The maize preligule band is subdivided into distinct domains with contrasting cellular properties prior to ligule outgrowth.Development (Cambridge, England) · 2023Article
- The phosphoinositide signature guides the final step of plant cytokinesis.Science advances · 2023Article
- Cortical polarity ensures its own asymmetric inheritance in the stomatal lineage to pattern the leaf surface.Science (New York, N.Y.) · 2023Article
- The OPAQUE1/DISCORDIA2 myosin XI is required for phragmoplast guidance during asymmetric cell division in maize.The Plant cell · 2023Article
- Cortical microtubules contribute to division plane positioning during telophase in maize.The Plant cell · 2023Article
- The localization of PHRAGMOPLAST ORIENTING KINESIN1 at the division site depends on the microtubule-binding proteins TANGLED1 and AUXIN-INDUCED IN ROOT CULTURES9 in Arabidopsis.The Plant cell · 2022Article
- Defects in division plane positioning in the root meristematic zone affect cell organization in the differentiation zone.Journal of cell science · 2022Article
- CLASP balances two competing cell division plane cues during leaf development.Nature plants · 2022Article
- Division site determination during asymmetric cell division in plants.The Plant cell · 2022Review
- A rich and bountiful harvest: Key discoveries in plant cell biology.The Plant cell · 2022Review
- The bryophytes Physcomitrium patens and Marchantia polymorpha as model systems for studying evolutionary cell and developmental biology in plants.The Plant cell · 2022Review
17 more citing papers are in PubMed but not listed here.
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5 authors.
Funding
Abstract
backgroundIn premitotic plant cells, the future division plane is predicted by a cortical ring of microtubules and F-actin called the preprophase band (PPB). The PPB persists throughout prophase, but is disassembled upon nuclear-envelope breakdown as the mitotic spindle forms. Following nuclear division, a cytokinetic phragmoplast forms between the daughter nuclei and expands laterally to attach the new cell wall at the former PPB site. A variety of observations suggest that expanding phragmoplasts are actively guided to the former PPB site, but little is known about how plant cells "remember" this site after PPB disassembly.
resultsIn premitotic plant cells, Arabidopsis TANGLED fused to YFP (AtTAN::YFP) colocalizes at the future division plane with PPBs. Strikingly, cortical AtTAN::YFP rings persist after PPB disassembly, marking the division plane throughout mitosis and cytokinesis. The AtTAN::YFP ring is relatively broad during preprophase/prophase and mitosis; narrows to become a sharper, more punctate ring during cytokinesis; and then rapidly disassembles upon completion of cytokinesis. The initial recruitment of AtTAN::YFP to the division plane requires microtubules and the kinesins POK1 and POK2, but subsequent maintenance of AtTAN::YFP rings appears to be microtubule independent. Consistent with the localization data, analysis of Arabidopsis tan mutants shows that AtTAN plays a role in guidance of expanding phragmoplasts to the former PPB site.
conclusionsAtTAN is implicated as a component of a cortical guidance cue that remains behind when the PPB is disassembled and directs the expanding phragmoplast to the former PPB site during cytokinesis.
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