Evidence map›Paper›PMID 17964134›Full record

ReviewCurrent opinion in structural biology2007

Electron tomography of viruses.

Sriram Subramaniam, Alberto Bartesaghi, Jun Liu, Adam E Bennett, Rachid Sougrat

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in structural biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Integrative Approaches to Study Virus Structures.Sub-cellular biochemistry · 2024
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Native immunogold labeling of cell surface proteins and viral glycoproteins for cryo-electron microscopy and cryo-electron tomography applications.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2015
    Article
  14. Article
  15. Magic angle spinning NMR of viruses.Progress in nuclear magnetic resonance spectroscopy · 2015
    Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sriram SubramaniamLaboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, United States. ss1@nih.gov <ss1@nih.gov>
Alberto Bartesaghi
Jun Liu
Adam E Bennett
Rachid Sougrat
National Cancer Institute · USNational Institutes of Health · USCenter for Cancer Research · US

Funding

Imaging cellular assemblies with three-dimensional EMZ01BC010278 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI SUBRAMANIAM, SRIRAM · 1999 to 2008
$1.1M
Intramural NIH HHS Z01 BC010278
6 · The paper itself

Abstract

Understanding the molecular architectures of enveloped and complex viruses is a challenging frontier in structural biology. In these viruses, the structural and compositional variation from one viral particle to another generally precludes the use of either crystallization or image averaging procedures that have been successfully implemented in the past for highly symmetric viruses. While advances in cryo electron tomography of unstained specimens provide new opportunities for identification and molecular averaging of individual subcomponents such as the surface glycoprotein spikes on purified viruses, electron tomography of stained and plunge-frozen cells is being used to visualize the cellular context of viral entry and replication. Here, we review recent developments in both areas as they relate to our understanding of the biology of heterogeneous and pleiomorphic viruses.

Indexed as

AnimalsAntibodies, ViralHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMicroscopy, ElectronModels, MolecularVirusesAntibodies, Viral

Identifiers

PMID17964134
PMCPMC2121662
OpenAlexW1987243391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.