ArticleClinical biochemistry2008
Serum interferon-gamma-inducible protein 10 level was increased in myocardial infarction patients, and negatively correlated with infarct size.
Article in Clinical biochemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 24 citations in OpenAlex.
- Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial.Journal of thrombosis and thrombolysis · 2012Trial
- Olmesartan reduces arterial stiffness and serum adipocyte fatty acid-binding protein in hypertensive patients.Heart and vessels · 2011Trial
- Human Bone Marrow Mesenchymal Stem Cells Promote the M2 Phenotype in Macrophages Derived from STEMI Patients.International journal of molecular sciences · 2023Article
- CXCL10 May Be Responsible for Susceptibility to Pulmonary Embolism in COVID-19 Patients.Journal of inflammation research · 2023Article
- Circulating Cytokines in Myocardial Infarction Are Associated With Coronary Blood Flow.Frontiers in immunology · 2022Article
- In vitro model of perimenopausal depression implicates steroid metabolic and proinflammatory genes.Molecular psychiatry · 2021Article
- The Role of CXCR3 and Associated Chemokines in the Development of Atherosclerosis and During Myocardial Infarction.Frontiers in immunology · 2018Review
- Temporal changes in biomarkers and their relationships to reperfusion and to clinical outcomes among patients with ST segment elevation myocardial infarction.Journal of thrombosis and thrombolysis · 2016Article
- The CXCL10/CXCR3 Axis and Cardiac Inflammation: Implications for Immunotherapy to Treat Infectious and Noninfectious Diseases of the Heart.Journal of immunology research · 2016Review
- The multifaceted functions of CXCL10 in cardiovascular disease.BioMed research international · 2014Review
- Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women.PloS one · 2013Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe examined the serum levels of interferon-gamma-inducible protein 10 (IP-10), an inflammation-induced chemokine, in acute myocardial infarction (AMI). DESIGN AND
methodsThe subjects were 33 AMI patients, 20 stable angina pectoris patients (AP) and 20 normal subjects. In AMI patients, blood samples were collected before percutaneous coronary intervention (PCI) and on days 3, 7 and 28.
resultsPatients with AMI showed significantly higher serum IP-10 levels (137.5+/-79.8 pg/mL) than control subjects (91.2+/-40.1 pg/mL) and patients with AP (93.3+/-41.1 pg/mL). The serum IP-10 level before PCI was negatively correlated with infarct size, as indicated by cumulative release of creatine kinase (CK) and peak CK and its isoenzyme CK-MB. Stepwise multiple regression analysis revealed that the serum IP-10 level before PCI was an independent predictor of cumulative CK release.
conclusionsThe serum IP-10 level was increased in AMI, and a higher level of serum IP-10 before PCI may be informative regarding infarct size.
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