ArticleEuropean journal of applied physiology2008
Body temperature and its effect on leukocyte mobilization, cytokines and markers of neutrophil activation during and after exercise.
Article in European journal of applied physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 85 citations in OpenAlex.
- Docosahexaenoic diet supplementation, exercise and temperature affect cytokine production by lipopolysaccharide-stimulated mononuclear cells.Journal of physiology and biochemistry · 2016Trial
- Mediators of monocyte migration in response to recovery modalities following resistance exercise.Mediators of inflammation · 2014Trial
- Considering evolved heat tolerance helps predict the immunological consequences of climate change.Seminars in immunopathology · 2026Review
- Impact of moderate environmental heat stress during running exercise on circulating markers of gastrointestinal integrity in endurance athletes.Physiological reports · 2025Article
- The Therapeutic Potential of Physical Exercise in Cancer: The Role of Chemokines.International journal of molecular sciences · 2024Review
- Acute ingestion of Ibuprofen does not influence the release of IL-6 or improve self-paced exercise in the heat despite altering cortical activity.European journal of applied physiology · 2024Article
- Blood-Based Biomarkers for Managing Workload in Athletes: Perspectives for Research on Emerging Biomarkers.Sports medicine (Auckland, N.Z.) · 2023Review
- Haematological, Biochemical and Hormonal Biomarkers of Heat Intolerance in Military Personnel.Biology · 2021Article
- Recovery-Stress Response of Blood-Based Biomarkers.International journal of environmental research and public health · 2021Article
- Impact of Exercise Intensity on Calprotectin Levels in Healthy Volunteers and Patients with Inflammatory Rheumatic Diseases.Life (Basel, Switzerland) · 2021Review
- Post-exercise Cold Water Immersion Effects on Physiological Adaptations to Resistance Training and the Underlying Mechanisms in Skeletal Muscle: A Narrative Review.Frontiers in sports and active living · 2021Review
- Tumor necrosis factor-α, TNF receptor, and soluble TNF receptor responses to aerobic exercise in the heat.Cytokine: X · 2020Article
- Characterization and Modulation of Systemic Inflammatory Response to Exhaustive Exercise in Relation to Oxidative Stress.Antioxidants (Basel, Switzerland) · 2020Review
- Chronic Inflammation as an Immunological Abnormality and Effectiveness of Exercise.Biomolecules · 2019Review
- The Influence of Post-Exercise Cold-Water Immersion on Adaptive Responses to Exercise: A Review of the Literature.Sports medicine (Auckland, N.Z.) · 2018Review
- Immune Response in Women during Exercise in the Heat: A Spotlight on Oral Contraception.Journal of sports science & medicine · 2018Article
- Pro- and anti-inflammatory cytokine responses to a 164-km road cycle ride in a hot environment.European journal of applied physiology · 2016Article
- Exercise, immune function and respiratory infection: An update on the influence of training and environmental stress.Immunology and cell biology · 2016Review
- Physical inactivity and low fitness deserve more attention to alter cancer risk and prognosis.Cancer prevention research (Philadelphia, Pa.) · 2015Review
- TNF-α and TNFR1 responses to recovery therapies following acute resistance exercise.Frontiers in physiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the influence of rectal temperature on the immune system during and after exercise. Ten well-trained male cyclists completed exercise trials (90 min cycling at 60% VO(2max) + 16.1 - km time trial) on three separate occasions: once in 18 degrees C and twice in 32 degrees C. Twenty minutes after the trials in 32 degrees C, the cyclists sat for approximately 20 min in cold water (14 degrees C) on one occasion, whereas on another occasion they sat at room temperature. Rectal temperature increased significantly during cycling in both conditions, and was significantly higher after cycling in 32 degrees C than in 18 degrees C (P < 0.05). Leukocyte counts increased significantly during cycling but did not differ between the conditions. The concentrations of serum interleukin (IL)-6, IL-8 and IL-10, plasma catecholamines, granulocyte-colony stimulating factor, myeloperoxidase and calprotectin increased significantly following cycling in both conditions. The concentrations of serum IL-8 (25%), IL-10 (120%), IL-1 receptor antagonist (70%), tumour necrosis factor-alpha (17%), plasma myeloperoxidase (26%) and norepinephrine (130%) were significantly higher after cycling in 32 degrees C than in 18 degrees C. During recovery from exercise in 32 degrees C, rectal temperature was significantly lower in response to sitting in cold water than at room temperature. However, immune changes during 90 min of recovery did not differ significantly between sitting in cold water and at room temperature. The greater rise in rectal temperature during exercise in 32 degrees C increased the concentrations of serum IL-8, IL-10, IL-1ra, TNF-alpha and plasma myeloperoxidase, whereas the greater decline in rectal temperature during cold water immersion after exercise did not affect immune responses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.