ArticleNucleic acids research2008
CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data.
Article in Nucleic acids research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it, 146 citations in OpenAlex.
- Pooled it
- Navigating through toxicological data: review of toxicological databases and sources in the interdisciplinary context including-chemicals, cosmetics, pharmaceuticals and forensics.Archives of toxicology · 2026Review
- Carcinogenicity prediction via multi-task learning of cross-organ representations with attention mechanisms.Briefings in bioinformatics · 2026Article
- HepatoToxicity Portal (HTP): an integrated database of drug-induced hepatotoxicity knowledgebase and graph neural network-based prediction model.Journal of cheminformatics · 2025Article
- Gene-environment interactions within a precision environmental health framework.Cell genomics · 2024Review
- Advancing Drug Safety in Drug Development: Bridging Computational Predictions for Enhanced Toxicity Prediction.Chemical research in toxicology · 2024Review
- A Case for Accelerating Standards to Achieve the FAIR Principles of Environmental Health Research Experimental Data.Environmental health perspectives · 2023Article
- Short-term in vivo testing to discriminate genotoxic carcinogens from non-genotoxic carcinogens and non-carcinogens using next-generation RNA sequencing, DNA microarray, and qPCR.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2023Review
- Using Prior Toxicological Data to Support Dose-Response Assessment─Identifying Plausible Prior Distributions for Dichotomous Dose-Response Models.Environmental science & technology · 2022Article
- Using phosphate amendments to reduce bioaccessible Pb in contaminated soils: A meta-analysis.Frontiers in soil science · 2022Article
- CEBS update: curated toxicology database with enhanced tools for data integration.Nucleic acids research · 2022Article
- Grouping of UVCB substances with dose-response transcriptomics data from human cell-based assays.ALTEX · 2022Article
- Effect of ondansetron on reducing ICU mortality in patients with acute kidney injury.Scientific reports · 2021Article
- Review
- Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects.Nanomaterials (Basel, Switzerland) · 2020Review
- Gene sequencing and expression of Raf-1 in lymphatic metastasis of hypopharyngeal carcinoma.Cancer biomarkers : section A of Disease markers · 2020Article
- The effect of ferulic acid against lead-induced oxidative stress and DNA damage in kidney and testes of rats.Environmental science and pollution research international · 2019Article
- Interactive Toxicogenomics: Gene set discovery, clustering and analysis in Toxygates.Scientific reports · 2017Article
- CEBS: a comprehensive annotated database of toxicological data.Nucleic acids research · 2017Article
- Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells.Nucleic acids research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 1 institution in 1 country.
Funding
Abstract
CEBS (Chemical Effects in Biological Systems) is an integrated public repository for toxicogenomics data, including the study design and timeline, clinical chemistry and histopathology findings and microarray and proteomics data. CEBS contains data derived from studies of chemicals and of genetic alterations, and is compatible with clinical and environmental studies. CEBS is designed to permit the user to query the data using the study conditions, the subject responses and then, having identified an appropriate set of subjects, to move to the microarray module of CEBS to carry out gene signature and pathway analysis. Scope of CEBS: CEBS currently holds 22 studies of rats, four studies of mice and one study of Caenorhabditis elegans. CEBS can also accommodate data from studies of human subjects. Toxicogenomics studies currently in CEBS comprise over 4000 microarray hybridizations, and 75 2D gel images annotated with protein identification performed by MALDI and MS/MS. CEBS contains raw microarray data collected in accordance with MIAME guidelines and provides tools for data selection, pre-processing and analysis resulting in annotated lists of genes of interest. Additionally, clinical chemistry and histopathology findings from over 1500 animals are included in CEBS. CEBS/BID: The BID (Biomedical Investigation Database) is another component of the CEBS system. BID is a relational database used to load and curate study data prior to export to CEBS, in addition to capturing and displaying novel data types such as PCR data, or additional fields of interest, including those defined by the HESI Toxicogenomics Committee (in preparation). BID has been shared with Health Canada and the US Environmental Protection Agency. CEBS is available at http://cebs.niehs.nih.gov. BID can be accessed via the user interface from https://dir-apps.niehs.nih.gov/arc/. Requests for a copy of BID and for depositing data into CEBS or BID are available at http://www.niehs.nih.gov/cebs-df/.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.