ArticleEnvironmental research2008
Scalp hair and urine mercury content of children in the Northeast United States: the New England Children's Amalgam Trial.
Article in Environmental research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 48 citations in OpenAlex.
- Fish and Seafood Safety: Human Exposure to Toxic Metals from the Aquatic Environment and Fish in Central Asia.International journal of molecular sciences · 2024Review
- Association between dental amalgam restoration and urine mercury concentrations among young women: a cross-sectional study.Journal of Yeungnam medical science · 2023Article
- Mercury Hair Concentration among Primary School Children in Malaysia.Children (Basel, Switzerland) · 2017Article
- Severe dermatitis might be caused by a cross-reaction between nickel and palladium and dental amalgam resolved following removal of dental restorations.Clinical case reports · 2017Article
- The dental amalgam toxicity fear: a myth or actuality.Toxicology international · 2012Article
- Methodological considerations with the use of urine samples for assessment of mercury excretion and markers of renal damage.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2010Article
- Mercury exposure and children's health.Current problems in pediatric and adolescent health care · 2010Review
- Nephrotoxicity, neurotoxicity, and mercury exposure among children with and without dental amalgam fillings.International journal of hygiene and environmental health · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
unlabelledChildren may be at particular risk from toxic effects of mercury (Hg). Previous studies of hair (organic) and urine (inorganic) Hg levels in US children were unable to assess Hg levels while accounting for exposure to amalgam dental restorations. This analysis describes, over a 5-year period, levels and correlates/predictors of scalp hair (H-Hg) and urinary (U-Hg) mercury in 534 New England Children's Amalgam Trial (NECAT) participants, aged 6-10 years and without exposure to dental amalgam at baseline.
resultsMean H-Hg levels were between 0.3 and 0.4 microg/g over 5 years. 17-29% of children had H-Hg levels > or = 0.5 microg/g, and 5.0 to 8.5% of children had levels > or = 1 microg/g, in any given study year. In adjusted models, fish consumption frequency was the most robust predictor of high H-Hg. U-Hg mean levels were between 0.7 and 0.9 microg/g creatinine over two years. The percentage of those with U-Hg > or 2.3 microg/g creatinine ranged from 4% to 6%. Number of amalgam restorations had a significant dose-response relationship with U-Hg level. Daily gum chewing in the presence of amalgam was associated with high U-Hg.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.