Evidence map›Paper›PMID 17961504›Full record

ReviewBiochimica et biophysica acta2007

Solution NMR of membrane proteins in bilayer mimics: small is beautiful, but sometimes bigger is better.

Sébastien F Poget, Mark E Girvin

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Article
  2. The Magnetosome Protein, Mms6 fromInternational journal of molecular sciences · 2022
    Article
  3. Article
  4. Review
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  8. Article
  9. Review
  10. Article
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  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Discovery of novel membrane binding structures and functions.Biochemistry and cell biology = Biochimie et biologie cellulaire · 2014
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sébastien F PogetBiochemistry Department, Albert Einstein College of Medicine, 1300 Morris Park Ave. Bronx, NY 10461, USA.
Mark E Girvin

Funding

900 MHz NMR Spectrometer for Structural BiologyP41GM066354 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI COWBURN, DAVID · 2002 to 2006
$4.7M
Structural Analysis of Multidrug TransportR01GM072085 · NIGMS · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI GIRVIN, MARK E. · 2004 to 2014
$2.7M
NIGMS NIH HHS GM66354NIGMS NIH HHS GM72085NIGMS NIH HHS P41 GM066354NIGMS NIH HHS R01 GM072085
6 · The paper itself

Abstract

Considerable progress has been made recently on solution NMR studies of multi-transmembrane helix membrane protein systems of increasing size. Careful correlation of structure with function has validated the physiological relevance of these studies in detergent micelles. However, larger micelle and bicelle systems are sometimes required to stabilize the active forms of dynamic membrane proteins, such as the bacterial small multidrug resistance transporters. Even in these systems with aggregate molecular weights well over 100 kDa, solution NMR structural studies are feasible-but challenging.

Indexed as

MicellesMagnetic Resonance SpectroscopyMembrane ProteinsMembrane ProteinsMicelles

Identifiers

PMID17961504
PMCPMC2239318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.