ArticleJournal of clinical microbiology2008
Molecular epidemiology of Escherichia coli producing extended-spectrum beta-lactamases isolated in Rome, Italy.
Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed.
- Insights into antimicrobial resistance: dissemination and molecular epidemiology of carbapenemase and AmpC genes in uropathogenic Escherichia coli.BMC microbiology · 2026Article
- Novel insights into antimicrobial-resistant, virulent and biofilm-formingFrontiers in microbiology · 2025Article
- F18:A-:B1 Plasmids CarryingAntibiotics (Basel, Switzerland) · 2023Article
- Occurrence of Extended Spectrum Cephalosporin-, Carbapenem- and Colistin-Resistant Gram-Negative Bacteria in Fresh Vegetables, an Increasing Human Health Concern in Algeria.Antibiotics (Basel, Switzerland) · 2022Article
- Exploring broilers and native fowls of Andaman and Nicobar Islands as a source of β-lactamase-producingFrontiers in veterinary science · 2022Article
- Predominance of genetically diverse ESBL Escherichia coli identified in resistance mapping of Vembanad Lake, the largest fresh-cum-brackishwater lake of India.Environmental science and pollution research international · 2021Article
- Extended-Spectrum-β-Lactamase- and AmpC-ProducingAntibiotics (Basel, Switzerland) · 2021Article
- Temporal, Spatial, and Genomic Analyses ofFrontiers in microbiology · 2021Article
- Molecularly defined extraintestinal pathogenicVirulence · 2020Article
- Novel Insights and Features of the NDM-5-Producing Escherichia coli Sequence Type 167 High-Risk Clone.mSphere · 2020Article
- Detection of two simultaneous outbreaks of Klebsiella pneumoniae coproducing OXA-48 and NDM-1 carbapenemases in a tertiary-care hospital in Valencia, Spain.New microbes and new infections · 2020Article
- Genomic Epidemiology ofFrontiers in veterinary science · 2020Article
- Genotypic validation of extended-spectrum β-lactamase and virulence factors in multidrug resistancePathogens and global health · 2019Article
- Article
- Characterization of cefotaxime resistant Escherichia coli isolated from broiler farms in Ecuador.PloS one · 2019Article
- Genomic Characterization of Extended-Spectrum Cephalosporin-ResistantFrontiers in microbiology · 2018Article
- Article
- Detection of emerging antibiotic resistance in bacteria isolated from subclinical mastitis in cattle in West Bengal.Veterinary world · 2017Article
- Diversity, virulence, and antimicrobial resistance of the KPC-producingMicrobial genomics · 2017Article
- Fatal sepsis by Klebsiella pneumoniae in a patient with systemic lupus erythematosus: the importance of postmortem microbiological examination for the ex post diagnosis of infection.International journal of legal medicine · 2015Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Escherichia coli strains producing extended-spectrum beta-lactamases (ESBLs) are a major problem in many different hospitals worldwide, causing outbreaks as well as sporadic infections. The prevalence of Escherichia coli ESBL producers was analyzed in a surveillance study performed on the population attending the Policlinico Umberto I, the largest university hospital in Rome, Italy. We also investigated genotypes, pathogenicity islands, and plasmids in the ESBL-positive E. coli isolates as further markers that are useful in describing the epidemiology of the infections. In this survey, 163 nonreplicate isolates of Escherichia coli were isolated from patients from 86 different wards, and 28 were confirmed as ESBL producers. A high prevalence (26/28) of CTX-M-15 producers was observed within the bacterial population circulating in this hospital, and the dissemination of this genetic trait was associated with the spread of related strains; however, these do not have the characteristics of a single epidemic clone spreading. The dissemination was also linked to horizontal transfer among the prevalent E. coli genotypes of multireplicon plasmids showing FIA, FIB, and FII replicons in various combinations, which are well adapted to the E. coli species. The analysis of related bacteria suggests a probable interpatient transmission occurring in several wards, causing small outbreaks.
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