ArticleDigestive diseases and sciences2008
Inhibitory effects of fermented brown rice on induction of acute colitis by dextran sulfate sodium in rats.
Article in Digestive diseases and sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 55 citations in OpenAlex.
- Efficacy of Fermented Brown Rice byJGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Fermented Rice Bran: A Promising Therapeutic Agent Against High-Fat Diet-Induced Metabolic Disorders.Food science & nutrition · 2026Article
- Anti-inflammatory effects of ethanolic extract fromFood & nutrition research · 2025Article
- Antidiarrheal Effect of Fermented Millet Bran on Diarrhea Induced by Senna Leaf in Mice.Foods (Basel, Switzerland) · 2022Article
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- Role of Short Chain Fatty Acid Receptors in Intestinal Physiology and Pathophysiology.Comprehensive Physiology · 2018Review
- Dietary Supplementation of Fermented Rice Bran Effectively Alleviates Dextran Sodium Sulfate-Induced Colitis in Mice.Nutrients · 2017Article
- Fermented rice bran supplementation mitigates metabolic syndrome in stroke-prone spontaneously hypertensive rats.BMC complementary and alternative medicine · 2016Article
- High protective efficacy of rice bran against human rotavirus diarrhea via enhancing probiotic growth, gut barrier function, and innate immunity.Scientific reports · 2015Article
- Bifidobacterium breve alters immune function and ameliorates DSS-induced inflammation in weanling rats.Pediatric research · 2015Article
- Diet in the pathogenesis and treatment of inflammatory bowel diseases.Gastroenterology · 2015Review
- Rice prolamin extract ameliorates acute murine colitis by inhibiting nuclear factor-kappa B and modulating intestinal apoptosis and cell proliferation.Clinical and experimental immunology · 2014Article
- Synergistic effect of fermented rice extracts on the probiotic and laxative properties of yoghurt in rats with loperamide-induced constipation.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Consumption of rice bran increases mucosal immunoglobulin A concentrations and numbers of intestinal Lactobacillus spp.Journal of medicinal food · 2012Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the pathogenic mechanisms of inflammatory bowel diseases are not fully understood, colonic microbiota may affect the induction of colonic inflammation, and some probiotics and prebiotics have been reported to suppress colitis. The inhibitory effects of brown rice fermented by Aspergillus oryzae (FBRA), a fiber-rich food, on the induction of acute colitis by dextran sulfate sodium (DSS) were examined. Feeding a 5% and 10% FBRA-containing diet significantly decreased the ulcer and erosion area in the rat colon stained with Alcian blue. In another experiment, 10% FBRA feeding decreased the ulcer index (percentage of the total length of ulcers in the full length of the colon) and colitis score, which were determined by macroscopic observation. It also decreased myeloperoxidase activity in the colonic mucosa. Viable cell numbers of Lactobacillus in the feces decreased after DSS administration and was reversely correlated with severity of colitis, while the cell number of Enterobacteriaceae increased after DSS treatment and was positively correlated with colitis severity. These results indicate that FBRA has a suppressive effect on the induction of colitis by DSS and suggest FBRA-mediated modification of colonic microbiota.
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