ArticlePloS one2007
Illusory stimuli can be used to identify retinal blind spots.
Article in PloS one, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Neural correlates of lateral modulation and perceptual filling-in in center-surround radial sinusoidal gratings: an fMRI study.Scientific reports · 2022Article
- Homeostatic plasticity in human extrastriate cortex following a simulated peripheral scotoma.Experimental brain research · 2017Article
- How cognitive neuroscience could be more biological-and what it might learn from clinical neuropsychology.Frontiers in human neuroscience · 2014Article
- A new taxonomy for perceptual filling-in.Brain research reviews · 2011Review
- Spatial alignment over retinal scotomas.Investigative ophthalmology & visual science · 2009Article
- The twinkle aftereffect is pre-cortical and is independent of filling-in.Journal of vision · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundIdentification of visual field loss in people with retinal disease is not straightforward as people with eye disease are frequently unaware of substantial deficits in their visual field, as a consequence of perceptual completion ("filling-in") of affected areas. METHODOLOGY: We attempted to induce a compelling visual illusion known as the induced twinkle after-effect (TwAE) in eight patients with retinal scotomas. Half of these patients experience filling-in of their scotomas such that they are unaware of the presence of their scotoma, and conventional campimetric techniques can not be used to identify their vision loss. The region of the TwAE was compared to microperimetry maps of the retinal lesion. PRINCIPAL
findingsSix of our eight participants experienced the TwAE. This effect occurred in three of the four people who filled-in their scotoma. The boundary of the TwAE showed good agreement with the boundary of lesion, as determined by microperimetry.
conclusionFor the first time, we have determined vision loss by asking patients to report the presence of an illusory percept in blind areas, rather than the absence of a real stimulus. This illusory technique is quick, accurate and not subject to the effects of filling-in.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.