ReviewSeminars in immunopathology2007
Role of T cells and dendritic cells in glomerular immunopathology.
Review in Seminars in immunopathology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 60 citations in OpenAlex.
- Pauci-Immune Endocapillary Proliferative Glomerulonephritis With Glomerular M2 Macrophage Infiltration.Kidney international reports · 2026Article
- Identification of Ribonuclease 6 as an immunoinflammatory key gene associated with the glomerular injury in diabetic nephropathy.Scientific reports · 2022Article
- Article
- The Pathogenesis of End-Stage Renal Disease from the Standpoint of the Theory of General Pathological Processes of Inflammation.International journal of molecular sciences · 2021Review
- Kidney injury in response to crystallization of calcium oxalate leads to rearrangement of the intrarenal T cell receptor delta immune repertoire.Journal of translational medicine · 2019Article
- Respiratory Syncytial Virus Aggravates Renal Injury through Cytokines and Direct Renal Injury.Frontiers in cellular and infection microbiology · 2016Article
- The role of Th1 and Th17 cells in glomerulonephritis.Journal of nephropathology · 2015Review
- What is the best way to measure renal fibrosis?: A pathologist's perspective.Kidney international supplements · 2014Review
- Dendritic cells and macrophages in the kidney: a spectrum of good and evil.Nature reviews. Nephrology · 2014Review
- Susceptibility quantitative trait loci for pathogenic leucocytosis in SCG/Kj mice, a spontaneously occurring crescentic glomerulonephritis and vasculitis model.Clinical and experimental immunology · 2014Article
- Exclusive CX3CR1 dependence of kidney DCs impacts glomerulonephritis progression.The Journal of clinical investigation · 2013Article
- A Lectin-EGF antibody promotes regulatory T cells and attenuates nephrotoxic nephritis via DC-SIGN on dendritic cells.Journal of translational medicine · 2013Article
- CD11c⁺ cells partially mediate the renoprotective effect induced by bone marrow-derived mesenchymal stem cells.PloS one · 2013Article
- Regulatory T cells use programmed death 1 ligands to directly suppress autoreactive B cells in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Human renal cell carcinoma induces a dendritic cell subset that uses T-cell crosstalk for tumor-permissive milieu alterations.The American journal of pathology · 2011Article
- Kidney dendritic cells in acute and chronic renal disease.International journal of experimental pathology · 2011Review
- The beneficial effects of statin therapy may not apply to all forms of crescentic glomerulonephritis.The American journal of pathology · 2011Article
- Kidney Dendritic Cells Become Pathogenic during Crescentic Glomerulonephritis with Proteinuria.Journal of the American Society of Nephrology : JASN · 2011Article
- Mechanistic connection between inflammation and fibrosis.Kidney international. Supplement · 2010Review
- Renal fibrosis: novel insights into mechanisms and therapeutic targets.Nature reviews. Nephrology · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inappropriate T cell responses cause the four classical types of hypersensitivity immune reactions. All of these can target the kidney and cause distinct forms of glomerulonephritis. CD4(+) T cells can mediate glomerular immunopathology by cytokine secretion, by activating effector cells such as macrophages or by inducing auto-antibodies or immune-complexes. Cytotoxic CD8(+) T cell responses and failure of regulatory T cells may represent two additional types of anti-renal hypersensitivity. T cell activation is critically dependent on dendritic cells (DC), whose role in renal disease appears to be protective, but underlying mechanisms are largely unknown. In this paper, we summarized mechanistic information from rodent models on the roles of DC and T cells in glomerular immunopathology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.