ReviewSports medicine (Auckland, N.Z.)2007
Physical activity before and after diagnosis of colorectal cancer: disease risk, clinical outcomes, response pathways and biomarkers.
Review in Sports medicine (Auckland, N.Z.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Systematic review of pre-operative exercise in colorectal cancer patients.Techniques in coloproctology · 2016Pooled it
- A prospective, multicenter pilot study to investigate the feasibility and safety of a 1-year controlled exercise training after adjuvant chemotherapy in colorectal cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Trial
- Article
- Review
- Article
- Short-term pre-operative high-intensity interval training does not improve fitness of colorectal cancer patients.Scandinavian journal of medicine & science in sports · 2019Article
- Environments Associated with Moderate-to-Vigorous Physical Activity and Sedentary Behavior of Colorectal Cancer Survivors.International journal of behavioral medicine · 2017Article
- How Can Physical Activity Referral Rates for Breast Cancer Patients be Increased?Frontiers in oncology · 2016Article
- Epidemiological transition of colorectal cancer in developing countries: environmental factors, molecular pathways, and opportunities for prevention.World journal of gastroenterology · 2014Review
- Physical activity for cancer patients: clinical risk assessment for exercise clearance and prescription.Canadian family physician Medecin de famille canadien · 2012Article
- Potential for prostate cancer prevention through physical activity.World journal of urology · 2012Review
- Regulation of colon cancer recurrence and development of therapeutic strategies.World journal of gastrointestinal pathophysiology · 2012Article
- The physical activity level in female affects colon transit time.Journal of neurogastroenterology and motility · 2012Article
- p53, aerobic metabolism, and cancer.Antioxidants & redox signaling · 2011Review
- Physical activity in the prevention and treatment of colorectal carcinoma.Deutsches Arzteblatt international · 2009Review
- Cardiorespiratory fitness and digestive cancer mortality: findings from the aerobics center longitudinal study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2009Article
- Recreational physical activity modifies the association between a common GH1 polymorphism and colorectal cancer risk.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2008Article
- Physical activity, sedentary behavior, and the risk of colon and rectal cancer in the NIH-AARP Diet and Health Study.Cancer causes & control : CCC · 2008Article
- Exercise in prevention and management of cancer.Current treatment options in oncology · 2008Review
- Importance of frequency, intensity, time and type (FITT) in physical activity assessment for epidemiological research.Canadian journal of public health = Revue canadienne de sante publiqueArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physical inactivity may be responsible for 13-14% of colon cancer, an attributable risk greater than family history. Epidemiological evidence shows an association between occupational and recreational physical activity and colon cancer, but has not established whether physical activity is protective against low-risk or more advanced adenomas. The evidence is inconclusive as to whether physical activity protects against rectal cancer and is conflicting with respect to whether physical activity has equal effects on male and female risk of colorectal cancer. The effect of exercise 'interventions' on the risk of colorectal cancer is currently not known. Also, although inferences can be made from epidemiological studies, no optimal exercise regimen can be confidently prescribed for protection against colorectal cancer. There is little available evidence for the benefits of physical activity before diagnosis of colorectal cancer for disease-specific survival and prognosis, and the clinical effects of an exercise intervention after diagnosis have not been investigated. There is some evidence that improvements in cardiorespiratory fitness reduce adverse effects from cancer treatment when physical activity is undertaken following diagnosis of colorectal cancer. Markers/mechanisms by which physical activity may protect against colorectal cancer and/or improve disease prognosis include gastrointestinal transit-time, chronic inflammation, immune function, insulin levels, insulin-like growth factors, genetics and obesity. Research evidence is, however, limited as to whether these markers are beneficially affected by physical activity, either before or after diagnosis of colorectal cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.