ArticleJournal of bacteriology2008
AvrAC(Xcc8004), a type III effector with a leucine-rich repeat domain from Xanthomonas campestris pathovar campestris confers avirulence in vascular tissues of Arabidopsis thaliana ecotype Col-0.
Article in Journal of bacteriology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed.
- Identification of protein secretion systems and type III effectors in wood-associated bacteria of the genusMicrobiology spectrum · 2026Article
- Salicylic acid-mediated competitive regulation of xylem vessel formation and defense responses in Arabidopsis thaliana.Plant & cell physiology · 2025Article
- Functional Analysis of Type III Effectors inPathogens (Basel, Switzerland) · 2024Article
- Identification of Parthenogenesis-Inducing Effector Proteins in Wolbachia.Genome biology and evolution · 2024Article
- Bacterial host adaptation through sequence and structural variations of a single type III effector gene.iScience · 2024Article
- Xanthomonas campestris VemR enhances the transcription of the T3SS key regulator HrpX via physical interaction with HrpG.Molecular plant pathology · 2023Article
- Comparative genomic analysis ofFrontiers in plant science · 2023Article
- Effector-triggered inhibition of nodulation: A rhizobial effector protease targets soybean kinase GmPBS1-1.Plant physiology · 2022Article
- ZAR1: Guardian of plant kinases.Frontiers in plant science · 2022Review
- Comparative genomics of the black rot pathogenPeerJ · 2022Article
- The Same against Many: AtCML8, a CaInternational journal of molecular sciences · 2021Article
- What the Wild Things Do: Mechanisms of Plant Host Manipulation by Bacterial Type III-Secreted Effector Proteins.Microorganisms · 2021Review
- Article
- Multiple Xanthomonas campestris pv. campestris 8004 type III effectors inhibit immunity induced by flg22.Planta · 2020Article
- Host-Pathogen Interactions betweenMicroorganisms · 2020Article
- Chemical Targeting and Manipulation of Type III Secretion in the Phytopathogen Xanthomonas campestris for Control of Disease.Applied and environmental microbiology · 2020Article
- Mechanistic insights into host adaptation, virulence and epidemiology of the phytopathogen Xanthomonas.FEMS microbiology reviews · 2020Review
- The roles of histidine kinases in sensing host plant and cell-cell communication signal in a phytopathogenic bacterium.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
- Complete Genome Sequence of Sequevar 14MFrontiers in microbiology · 2019Article
- RpfC regulates the expression of the key regulator hrpX of the hrp/T3SS system in Xanthomonas campestris pv. campestris.BMC microbiology · 2018Article
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Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Xanthomonas campestris pathovar campestris causes black rot, a vascular disease on cruciferous plants, including Arabidopsis thaliana. The gene XC1553 from X. campestris pv. campestris strain 8004 encodes a protein containing leucine-rich repeats (LRRs) and appears to be restricted to strains of X. campestris pv. campestris. LRRs are found in a number of type III-secreted effectors in plant and animal pathogens. These prompted us to investigate the role of the XC1553 gene in the interaction between X. campestris pv. campestris and A. thaliana. Translocation assays using the hypersensitive-reaction-inducing domain of X. campestris pv. campestris AvrBs1 as a reporter revealed that XC1553 is a type III effector. Infiltration of Arabidopsis leaf mesophyll with bacterial suspensions showed no differences between the wild-type strain and an XC1553 gene mutant; both strains induced disease symptoms on Kashmir and Col-0 ecotypes. However, a clear difference was observed when bacteria were introduced into the vascular system by piercing the central vein of leaves. In this case, the wild-type strain 8004 caused disease on the Kashmir ecotype, but not on ecotype Col-0; the XC1553 gene mutant became virulent on the Col-0 ecotype and still induced disease on the Kashmir ecotype. Altogether, these data show that the XC1553 gene, which was renamed avrAC(Xcc8004), functions as an avirulence gene whose product seems to be recognized in vascular tissues.
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