ArticleFEBS letters2007
Reproductive function for a C-terminus extended, male-transmitted cytochrome c oxidase subunit II protein expressed in both spermatozoa and eggs.
Article in FEBS letters, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 52 citations in OpenAlex.
- Demystifying the functions of the mitochondrial ORFan proteins in bivalves with doubly uniparental inheritance.Biology letters · 2025Article
- Mitochondrion-to-nucleus communication mediated by RNA export: a survey of potential mechanisms and players across eukaryotes.Biology letters · 2024Review
- The absence of canonical respiratory complex I subunits in male-type mitogenomes of three Donax species.Scientific reports · 2024Article
- A tale of two paths: The evolution of mitochondrial recombination in bivalves with doubly uniparental inheritance.The Journal of heredity · 2023Article
- Confirmation of the first intronic sequence in the bivalvian mitochondrial genome ofBiology letters · 2022Article
- The longest mitochondrial protein in metazoans is encoded by the male-transmitted mitogenome of the bivalveBiology letters · 2022Article
- Did doubly uniparental inheritance (DUI) of mtDNA originate as a cytoplasmic male sterility (CMS) system?BioEssays : news and reviews in molecular, cellular and developmental biology · 2022Article
- Molluscan mitochondrial genomes break the rules.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Unorthodox features in two venerid bivalves with doubly uniparental inheritance of mitochondria.Scientific reports · 2020Article
- Evolution and inheritance of animal mitochondrial DNA: rules and exceptions.Journal of biological research (Thessalonike, Greece) · 2017Review
- Article
- In silico analyses of mitochondrial ORFans in freshwater mussels (Bivalvia: Unionoida) provide a framework for future studies of their origin and function.BMC genomics · 2016Article
- Article
- The Complete Female- and Male-Transmitted Mitochondrial Genome of Meretrix lamarckii.PloS one · 2016Article
- Proteomic analysis of eggs from Mytilus edulis females differing in mitochondrial DNA transmission mode.Molecular & cellular proteomics : MCP · 2013Article
- Article
- Mitochondrial genomes and Doubly Uniparental Inheritance: new insights from Musculista senhousia sex-linked mitochondrial DNAs (Bivalvia Mytilidae).BMC genomics · 2011Article
- Novel protein genes in animal mtDNA: a new sex determination system in freshwater mussels (Bivalvia: Unionoida)?Molecular biology and evolution · 2011Article
- Evidence for a fourteenth mtDNA-encoded protein in the female-transmitted mtDNA of marine Mussels (Bivalvia: Mytilidae).PloS one · 2011Article
- Mitochondrial phylogenomics of the Bivalvia (Mollusca): searching for the origin and mitogenomic correlates of doubly uniparental inheritance of mtDNA.BMC evolutionary biology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 7 institutions in 2 countries.
Funding
Abstract
Our previous study documented expression of a male-transmitted cytochrome c oxidase subunit II protein (MCOX2), with a C-terminus extension (MCOX2e), in unionoidean bivalve testes and sperm mitochondria. Here, we present evidence demonstrating that MCOX2 is seasonally expressed in testis, with a peak shortly before fertilization that is independent of sperm density. MCOX2 is localized to the inner and outer sperm mitochondrial membranes and the MCOX2 antibody's epitope is conserved across >65 million years of evolution. We also demonstrate the presence of male-transmitted mtDNA and season-specific MCOX2 spatial variation in ovaries. We hypothesize that MCOX2 plays a role in reproduction through gamete maturation, fertilization and/or embryogenesis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.