ArticleExperimental eye research2008
Edinger--Westphal stimulated accommodative dynamics in anesthetized, middle-aged rhesus monkeys.
Article in Experimental eye research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Protein Disulfide Levels and Lens Elasticity Modulation: Applications for Presbyopia.Investigative ophthalmology & visual science · 2016Article
- Full-field accommodation in rhesus monkeys measured using infrared photorefraction.Investigative ophthalmology & visual science · 2012Article
- Influence of amplitude, starting point, and age on first- and second-order dynamics of Edinger-Westphal-stimulated accommodation in rhesus monkeys.Investigative ophthalmology & visual science · 2010Article
- Short-term adaptive modification of dynamic ocular accommodation.Investigative ophthalmology & visual science · 2009Article
- [Accommodation and presbyopia : part 1: physiology of accommodation and development of presbyopia].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The relationships between peak velocity and amplitude of Edinger-Westphal (EW) stimulated accommodation and disaccommodation were investigated in anesthetized, middle-aged rhesus monkeys. Accommodative responses were recorded at 30Hz with infrared photorefraction. Peak velocity of accommodation and disaccommodation increased linearly with stimulus amplitude. Peak velocities of accommodation continued to increase with stimulus amplitudes greater than required to produce the maximum response. The peak velocity of disaccommodation did not further increase with supramaximal stimulus amplitudes beyond that achieved with maximal stimulus amplitudes. Although maximum accommodative response amplitude is reduced in older rhesus monkeys, within the methodological constraints of this study, older monkeys appear to achieve accommodative and disaccommodative peak velocities similar to adolescent monkeys for the same response amplitudes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.