ReviewWorld journal of gastroenterology2007
Innate immunity in inflammatory bowel disease.
Review in World journal of gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 73 citations in OpenAlex.
- Integrated Analysis of Ulcerative Colitis Revealed an Association betweenDisease markers · 2022Article
- Effect of T. spiralis Serine protease inhibitors on TNBS-induced experimental colitis mediated by Macrophages.Scientific reports · 2020Article
- Applying nanomedicine in maladaptive inflammation and angiogenesis.Advanced drug delivery reviews · 2017Review
- Mesenchymal Stromal Cells and Toll-Like Receptor Priming: A Critical Review.Immune network · 2017Review
- Pharmacogenetics in inflammatory bowel disease: understanding treatment response and personalizing therapeutic strategies.Pharmacogenomics and personalized medicine · 2017Review
- Extracellular ATP mediates inflammatory responses in colitis via P2 × 7 receptor signaling.Scientific reports · 2016Article
- Schistosome-Derived Molecules as Modulating Actors of the Immune System and Promising Candidates to Treat Autoimmune and Inflammatory Diseases.Journal of immunology research · 2016Review
- Gingko biloba extract (Ginaton) ameliorates dextran sulfate sodium (DSS)-induced acute experimental colitis in mice via reducing IL-6/STAT3 and IL-23/IL-17.International journal of clinical and experimental medicine · 2015Article
- How the Intricate Interaction among Toll-Like Receptors, Microbiota, and Intestinal Immunity Can Influence Gastrointestinal Pathology.Journal of immunology research · 2015Review
- Role of the gut microbiota in inflammatory bowel disease pathogenesis: what have we learnt in the past 10 years?World journal of gastroenterology · 2014Review
- Haplotype analyses of DNA repair gene polymorphisms and their role in ulcerative colitis.PloS one · 2014Article
- Implication of intestinal VDR deficiency in inflammatory bowel disease.Biochimica et biophysica acta · 2013Article
- Creating diseases to understand what prevents them: genetic analysis of inflammation in the gastrointestinal tract.Current opinion in immunology · 2012Review
- Milk fat globule-epidermal growth factor 8 is decreased in intestinal epithelium of ulcerative colitis patients and thereby causes increased apoptosis and impaired wound healing.Molecular medicine (Cambridge, Mass.) · 2012Article
- Toll-like receptors as modulators of mesenchymal stem cells.Frontiers in immunology · 2012Article
- Extracellular matrix protein lumican regulates inflammation in a mouse model of colitis.Inflammatory bowel diseases · 2012Article
- Dietary fish oil and curcumin combine to modulate colonic cytokinetics and gene expression in dextran sodium sulphate-treated mice.The British journal of nutrition · 2011Article
- Innate immune sensors and gastrointestinal bacterial infections.Clinical & developmental immunology · 2011Review
- MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Dysregulation of inflammatory responses by chronic circadian disruption.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human intestinal tract is home to an enormous bacterial flora. The host defense against microorganisms can be divided into innate and adaptive immunity. The former is the most immediate line of response to immunologic challenges presented by bacteria, viruses, and fungi. The mucosal immune system has evolved to balance the need to respond to pathogens while co-existing with commensal bacteria and food antigens. In inflammatory bowel disease (IBD), this hyporesponsiveness or tolerance breaks down and inflammation supervenes driven by the intestinal microbial flora. Bacteria contain compounds and are recognized by a variety of receptors, including Toll-like receptors (TLRs) and NODs (a family of intracellular bacterial sensors) and are potent stimuli of innate immune responses. Several mutations in these receptors have been associated with development of IBD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.