ArticleWorld journal of gastroenterology2007
Emerging role of IL-23/IL-17 axis in H pylori-associated pathology.
Article in World journal of gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Association of IL-17 polymorphisms with gastric cancer risk in Asian populations.World journal of gastroenterology · 2015Pooled it
- Genetic polymorphisms and tissue expression of interleukin-22 associated with risk and therapeutic response of gastric mucosa-associated lymphoid tissue lymphoma.Blood cancer journal · 2014Trial
- Molecular Insights intoCancers · 2026Review
- Update on molecular pathogenesis ofWorld journal of gastrointestinal pathophysiology · 2025Review
- Strategies ofFrontiers in cellular and infection microbiology · 2024Review
- Dietary mercury intake, the IL23R rs10889677 polymorphism, and the risk of gastric cancer in a Korean population: a hospital-based case-control study.Epidemiology and health · 2024Article
- Review
- Relationship between active Helicobacter pylori infection and risk factors of cardiovascular diseases, a cross-sectional hospital-based study in a Sub-Saharan setting.BMC infectious diseases · 2022Article
- IL13 Acts Directly on Gastric Epithelial Cells to Promote Metaplasia Development During Chronic Gastritis.Cellular and molecular gastroenterology and hepatology · 2022Article
- The Roles of IL-17, IL-21, and IL-23 in theToxins · 2021Review
- From genes polymorphisms to mucosal expression of cytokines: evaluating IL-23/IL-17 axis in adult patients with gastritis.African health sciences · 2020Article
- Frequency distribution of IL-17A G197A (rs2275913) and IL-17F A7488G (rs763780) polymorphisms among healthy Sudanese population.BMC research notes · 2020Article
- Immunological Aspects of the Tumor Microenvironment and Epithelial-Mesenchymal Transition in Gastric Carcinogenesis.International journal of molecular sciences · 2020Review
- Stromal C-type lectin receptor COLEC12 integrates H. pylori, PGE2-EP2/4 axis and innate immunity in gastric diseases.Scientific reports · 2018Article
- Interleukin-17A Promotes Parietal Cell Atrophy by Inducing Apoptosis.Cellular and molecular gastroenterology and hepatology · 2018Article
- Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk.Mediators of inflammation · 2017Article
- Local Immune Response in Helicobacter pylori Infection.Medicine · 2016Article
- Role of interleukin-17 in chondrocytes of herniated intervertebral lumbar discs.Experimental and therapeutic medicine · 2015Article
- Comparative Immune Response in Children and Adults with H. pylori Infection.Journal of immunology research · 2015Review
- Defining the Roles of IFN-γ and IL-17A in Inflammation and Protection against Helicobacter pylori Infection.PloS one · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colonization of stomach by H pylori is followed by a marked infiltration of the mucosa with polymorphonuclear leukocytes, macrophages, and lymphocytes that very often remains asymptomatic, but in some circumstances can lead to the development of gastroduodenal ulceration, gastric carcinoma, and mucosa-associated lymphoid tissue lymphoma. The molecular mechanisms by which H pylori triggers and maintains the local immune response are complex, but there is evidence that cytokines produced by both immune and non-immune cells contribute to amplify the ongoing inflammation. H pylori infection is associated with a marked mucosal induction of T helper (Th) type 1 and Th17-type cytokines that is governed by specific antigen-presenting cell-derived molecules, such as interleukin (IL)-12 and IL-23. In this paper, we will review the available data on the expression and role of IL-23 and IL-17 in H pylori-related gastritis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.