Evidence map›Paper›PMID 17947425›Full record

ArticleGenetics2007

Association analysis of historical bread wheat germplasm using additive genetic covariance of relatives and population structure.

José Crossa, Juan Burgueño, Susanne Dreisigacker, Mateo Vargas, Sybil A Herrera-Foessel, Morten Lillemo, Ravi P Singh, Richard Trethowan, Marilyn Warburton, Jorge Franco and 3 more

Abstract readHistorical Article
In one paragraph

Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 157 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
157citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

157 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Genome-Wide Association Analysis of Fresh Maize.International journal of molecular sciences · 2025
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  12. Mining the Vavilov wheat diversity panel for new sources of adult plant resistance to stripe rust.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
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  14. Article
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  18. Review
  19. Article
  20. Article

97 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

José CrossaInternational Maize and Wheat Improvement Center (CIMMYT), 06600 México, DF, Mexico. j.crossa@cgiar.org
Juan Burgueño
Susanne Dreisigacker
Mateo Vargas
Sybil A Herrera-Foessel
Morten Lillemo
Ravi P Singh
Richard Trethowan
Marilyn Warburton
Jorge Franco
Matthew Reynolds
Jonathan H Crouch
Rodomiro Ortiz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linkage disequilibrium can be used for identifying associations between traits of interest and genetic markers. This study used mapped diversity array technology (DArT) markers to find associations with resistance to stem rust, leaf rust, yellow rust, and powdery mildew, plus grain yield in five historical wheat international multienvironment trials from the International Maize and Wheat Improvement Center (CIMMYT). Two linear mixed models were used to assess marker-trait associations incorporating information on population structure and covariance between relatives. An integrated map containing 813 DArT markers and 831 other markers was constructed. Several linkage disequilibrium clusters bearing multiple host plant resistance genes were found. Most of the associated markers were found in genomic regions where previous reports had found genes or quantitative trait loci (QTL) influencing the same traits, providing an independent validation of this approach. In addition, many new chromosome regions for disease resistance and grain yield were identified in the wheat genome. Phenotyping across up to 60 environments and years allowed modeling of genotype x environment interaction, thereby making possible the identification of markers contributing to both additive and additive x additive interaction effects of traits.

Indexed as

Chromosome MappingGenes, PlantGenetic MarkersHistory, 20th CenturyHistory, 21st CenturyLinear ModelsLinkage DisequilibriumModels, GeneticModels, StatisticalPhenotypePlant DiseasesQuantitative Trait LociTime FactorsTriticumGenetic Markers

Identifiers

PMID17947425
PMCPMC2147943

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.