Evidence map›Paper›PMID 17947413›Full record

ArticleGenetics2007

The extent of linkage disequilibrium in rice (Oryza sativa L.).

Kristie A Mather, Ana L Caicedo, Nicholas R Polato, Kenneth M Olsen, Susan McCouch, Michael D Purugganan

Abstract read
In one paragraph

Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 198 papers.

0numbers the graph read from it
0cells of the map it votes in
198citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

198 citing papers in PubMed.

  1. Candidate genes identification for internode length in rice via genome-wide association studies.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  16. GW3, encoding a member of the P450 subfamily, controls grain width by regulating the GATAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024
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138 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Kristie A MatherDepartment of Genetics, North Carolina State University, Raleigh 27695, USA.
Ana L Caicedo
Nicholas R Polato
Kenneth M Olsen
Susan McCouch
Michael D Purugganan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite its status as one of the world's major crops, linkage disequilibrium (LD) patterns have not been systematically characterized across the genome of Asian rice (Oryza sativa). Such information is critical to fully exploit the genome sequence for mapping complex traits using association techniques. Here we characterize LD in five 500-kb regions of the rice genome in three major cultivated rice varieties (indica, tropical japonica, and temperate japonica) and in the wild ancestor of Asian rice, Oryza rufipogon. Using unlinked SNPs to determine the amount of background linkage disequilibrium in each population, we find that the extent of LD is greatest in temperate japonica (probably >500 kb), followed by tropical japonica (approximately 150 kb) and indica (approximately 75 kb). LD extends over a shorter distance in O. rufipogon (<<40 kb) than in any of the O. sativa groups assayed here. The differences in the extent of LD among these groups are consistent with differences in outcrossing and recombination rate estimates. As well as heterogeneity between groups, our results suggest variation in LD patterns among genomic regions. We demonstrate the feasibility of genomewide association mapping in cultivated Asian rice using a modest number of SNPs.

Indexed as

Linkage DisequilibriumBase SequenceCrops, AgriculturalGenetic LinkageGenome, PlantMolecular Sequence DataOryzaPolymorphism, Single NucleotideRecombination, Genetic

Identifiers

PMID17947413
PMCPMC2219496

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.