ArticleGenetics2007
The blast resistance gene Pi37 encodes a nucleotide binding site leucine-rich repeat protein and is a member of a resistance gene cluster on rice chromosome 1.
Article in Genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.
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71 citing papers in PubMed, 1 synthesis or guideline pooled it, 232 citations in OpenAlex.
- Quantitative Trait Locus (QTL) meta-analysis and comparative genomics for candidate gene prediction in perennial ryegrass (Lolium perenne L.).BMC genetics · 2012Pooled it
- Genome-wide prediction of cloned disease resistance homologues across the Oryza genus.The plant genome · 2026Article
- Comparative genome assemblies reveal distinct allelic and structural variation at blast resistance loci in rice CT21375-F4-4 and Moroberekan.The plant genome · 2026Article
- Pan-NLRome analysis uncovers genetic diversity and evolutionary dynamics among rice, maize and sorghum.The plant genome · 2026Article
- Evaluating Blast Resistance of Huang-Huai Geng/Japonica Varieties Using Intragenic Markers.Rice (New York, N.Y.) · 2026Article
- Genome-Wide Association and Transcriptome Analyses Identify OsCBP606 as a Calmodulin-Mediated Susceptibility Gene to Magnaporthe oryzae in Rice.Rice (New York, N.Y.) · 2026Article
- Research Progress on Rice-Blast-Resistance-Related Genes.Plants (Basel, Switzerland) · 2025Review
- A century of advances in molecular genetics and breeding for sustainable resistance to rice blast disease.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- Status on Genetic Resistance to Rice Blast Disease in the Post-Genomic Era.Plants (Basel, Switzerland) · 2025Review
- Molecular breeding approaches for sustainable rice blast management: recent advances and challenges.Frontiers in plant science · 2025Review
- Allelic variation in rice blast resistance: a pathway to sustainable disease management.Molecular biology reports · 2024Review
- Refinement of rice blast disease resistance QTLs and gene networks through meta-QTL analysis.Scientific reports · 2024Article
- Pangenome-Wide Association Study and Transcriptome Analysis Reveal a Novel QTL and Candidate Genes Controlling both Panicle and Leaf Blast Resistance in Rice.Rice (New York, N.Y.) · 2024Article
- Influence of Two Hexose Transporters on Substrate Affinity and Pathogenicity inMicroorganisms · 2024Article
- Recent Advances in Effector Research ofBiomolecules · 2023Review
- Integrated Molecular and Bioinformatics Approaches for Disease-Related Genes in Plants.Plants (Basel, Switzerland) · 2023Review
- Approaches to Reduce Rice Blast Disease Using Knowledge from Host Resistance and Pathogen Pathogenicity.International journal of molecular sciences · 2023Review
- Available cloned genes and markers for genetic improvement of biotic stress resistance in rice.Frontiers in plant science · 2023Review
- A chromosome-level genome assembly of an early matured aromaticFrontiers in plant science · 2023Article
- Advancement in the Breeding, Biotechnological and Genomic Tools towards Development of Durable Genetic Resistance against the Rice Blast Disease.Plants (Basel, Switzerland) · 2022Review
11 more citing papers are in PubMed but not listed here.
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6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The resistance (R) gene Pi37, present in the rice cultivar St. No. 1, was isolated by an in silico map-based cloning procedure. The equivalent genetic region in Nipponbare contains four nucleotide binding site-leucine-rich repeat (NBS-LRR) type loci. These four candidates for Pi37 (Pi37-1, -2, -3, and -4) were amplified separately from St. No. 1 via long-range PCR, and cloned into a binary vector. Each construct was individually transformed into the highly blast susceptible cultivar Q1063. The subsequent complementation analysis revealed Pi37-3 to be the functional gene, while -1, -2, and -4 are probably pseudogenes. Pi37 encodes a 1290 peptide NBS-LRR product, and the presence of substitutions at two sites in the NBS region (V239A and I247M) is associated with the resistance phenotype. Semiquantitative expression analysis showed that in St. No. 1, Pi37 was constitutively expressed and only slightly induced by blast infection. Transient expression experiments indicated that the Pi37 product is restricted to the cytoplasm. Pi37-3 is thought to have evolved recently from -2, which in turn was derived from an ancestral -1 sequence. Pi37-4 is likely the most recently evolved member of the cluster and probably represents a duplication of -3. The four Pi37 paralogs are more closely related to maize rp1 than to any of the currently isolated rice blast R genes Pita, Pib, Pi9, Pi2, Piz-t, and Pi36.
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