SynthesisThe Cochrane database of systematic reviews2007
Single versus multiple visits for endodontic treatment of permanent teeth.
Synthesis in The Cochrane database of systematic reviews, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 7 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Incidence of postoperative pain after single-visit and multiple-visit root canal therapy: a systematic review.BMC oral health · 2025Pooled it
- Single versus multiple visits for endodontic treatment of permanent teeth.The Cochrane database of systematic reviews · 2022Pooled it
- Current strategies for conservative endodontic access cavity preparation techniques-systematic review, meta-analysis, and decision-making protocol.Clinical oral investigations · 2021Pooled it
- Single-visit or multiple-visit root canal treatment: systematic review, meta-analysis and trial sequential analysis.BMJ open · 2017Pooled it
- Single versus multiple visits for endodontic treatment of permanent teeth.The Cochrane database of systematic reviews · 2016Pooled it
- Irrigants for non-surgical root canal treatment in mature permanent teeth.The Cochrane database of systematic reviews · 2012Pooled it
- Hand and ultrasonic instrumentation for orthograde root canal treatment of permanent teeth.Journal of applied oral science : revista FOBPooled it
- Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial.Pain research & management · 2020Trial
- Pain after single-visit root canal treatment with two single-file systems based on different kinematics--a prospective randomized multicenter clinical study.Clinical oral investigations · 2015Trial
- Incidence of post-obturation pain after single-visit versus multiple-visit non-surgical endodontic treatments.BMC oral health · 2015Trial
- Getting your publication right - Part 3 structuring a research manuscript: A guide to writing clinical trials.Journal of conservative dentistry and endodontics · 2026Review
- Success Rates in Single-Visit Versus Multiple-Visit Root Canal Treatments: A Prospective Study.Journal of pharmacy & bioallied sciences · 2025Article
- Anxiety among patients with single versus multiple visits for root canal treatment.Bioinformation · 2025Article
- Evaluation of Post-Operative Pain and Healing in Single-Visit versus Multiple-Visit Root Canal Therapy.Journal of pharmacy & bioallied sciences · 2024Article
- Endodontic Flare-Ups: An Update.Cureus · 2023Review
- Outcomes reporting in systematic reviews on non-surgical root canal treatment: A scoping review for the development of a core outcome set.International endodontic journal · 2022Article
- Influence of Tooth Factors and Procedural Errors on the Incidence and Severity of Post-Endodontic Pain: A Prospective Clinical Study.Dentistry journal · 2020Article
- 20 years - 20 highlights.Evidence-based dentistry · 2019Article
- Radiographic Quality of SingleIranian endodontic journal · 2018Article
- Postoperative Pain and Flare-Ups: Comparison of Incidence Between Single and Multiple Visit Pulpectomy in Primary Molars.Journal of clinical and diagnostic research : JCDR · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRoot canal treatment (RoCT), or endodontic treatment, is a common procedure in dentistry. The main indications for RoCT are irreversible pulpitis and necrosis of the dental pulp caused by carious processes, tooth cracks or chips, or dental trauma. Successful RoCT is characterised by an absence of symptoms and clinical signs in teeth without radiographic evidence of periodontal involvement. The success of RoCT depends on a series of variables related to the preoperative condition of the tooth, as well as the endodontic procedures.
objectivesTo compare the effectiveness of single- and multiple-visit RoCT, measured as tooth extraction due to endodontic problems and radiological success.To assess the difference in short- and long-term complications between single- and multiple-visit RoCT. SEARCH STRATEGY: The following databases were searched for relevant trials: Cochrane Oral Health Group's Trials Register, CENTRAL, MEDLINE, and EMBASE. Handsearching was performed for the major oral medicine journals. References of included studies and reviews were checked. Endodontics experts were contacted through e-mail. No language limitations were imposed. Date of last search was 6th March 2007. SELECTION CRITERIA: Randomised and quasi-randomised controlled trials of patients needing RoCT were included. Surgical endodontic treatment was excluded. The outcomes considered were the number of teeth extracted for endodontic problems; radiological success after at least 1 year, that is, absence of any periapical radiolucency; postoperative pain; painkiller use; swelling; or sinus track formation. DATA COLLECTION AND ANALYSIS: Data were collected using a specific extraction form. The validity of included studies was assessed on the basis of allocation concealment, blindness of the study, and loss of participants. Data were analysed by calculating risk ratios. When valid and relevant data were collected, a meta-analysis of the data was undertaken. MAIN
resultsTwelve randomised controlled trials were included in the review. Four studies had a low risk of bias, four a moderate risk, and another four had a high risk of bias. The frequency of radiological success and immediate postoperative pain were not significantly different between single- and multiple-visit RoCT. Patients undergoing single-visit RoCT reported a higher frequency of painkiller use and swelling, but the results for swelling were not significantly different between the two groups. We found no study that included tooth loss and sinus track formation among its primary outcomes. AUTHORS'
conclusionsNo difference exists in the effectiveness of RoCT, in terms of radiological success, between single- and multiple-visit RoCT. Most short- and long-term complications are also similar in terms of frequency, although patients undergoing a single visit may experience a slightly higher frequency of swelling and are significatively more likely to take painkillers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.