SynthesisThe Cochrane database of systematic reviews2007
Formula milk versus maternal breast milk for feeding preterm or low birth weight infants.
Synthesis in The Cochrane database of systematic reviews, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Feeding Interventions for Infants with Growth Failure in the First Six Months of Life: A Systematic Review.Nutrients · 2020Pooled it
- Formula versus maternal breast milk for feeding preterm or low birth weight infants.The Cochrane database of systematic reviews · 2019Pooled it
- Working group reports: evaluation of the evidence to support practice guidelines for nutritional care of preterm infants-the Pre-B Project.The American journal of clinical nutrition · 2016Pooled it
- Preterm infants fed fortified human milk receive less protein than they need.Journal of perinatology : official journal of the California Perinatal Association · 2009Trial
- Editorial: Feeding difficulties in newborn infants and new approaches in practice.Frontiers in pediatrics · 2024Article
- Addressing milk kinship in milk banking: experience from Singapore's first donor human milk bank.Singapore medical journal · 2023Article
- Effect of different feeding methods and gut microbiota on premature infants and clinical outcomes.Frontiers in nutrition · 2022Article
- Early Enteral Feeding in Preterm Infants: A Narrative Review of the Nutritional, Metabolic, and Developmental Benefits.Nutrients · 2021Review
- Article
- Longitudinal Analysis of Macronutrient Composition in Preterm and Term Human Milk: A Prospective Cohort Study.Nutrients · 2019Article
- Compliance with the "Baby-friendly Hospital Initiative for Neonatal Wards" in 36 countries.Maternal & child nutrition · 2019Article
- Comparative Effectiveness of Prophylactic Therapies for Necrotizing Enterocolitis in Preterm Infants: Protocol for a Network Meta-analysis of Randomized Trials.International journal of preventive medicine · 2018Article
- Direct Feeding at the Breast Is Associated with Breast Milk Feeding Duration among Preterm Infants.Nutrients · 2017Article
- Article
- Survey of nutritional practices during therapeutic hypothermia for hypoxic-ischaemic encephalopathy.BMJ paediatrics open · 2017Article
- Article
- Comparison of mid-infrared transmission spectroscopy with biochemical methods for the determination of macronutrients in human milk.Maternal & child nutrition · 2014Article
- Evidence-based feeding strategies before and after the development of necrotizing enterocolitis.Expert review of clinical immunology · 2014Review
- Predicting disease severity of necrotizing enterocolitis: how to identify infants for future novel therapies.Journal of clinical neonatology · 2014Review
- Feeding practices and necrotizing enterocolitis.Clinics in perinatology · 2013Review
Corrections and comments
- Updated by
- Update of
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMaternal breast milk may contain less nutrients than artificial formula milk but may confer important non-nutrient advantages for preterm or low birth weight infants.
objectivesTo determine the effect of feeding with formula milk compared with maternal breast milk on rate of growth and developmental outcomes in preterm or low birth weight infants. SEARCH STRATEGY: The standard search strategy of the Cochrane Neonatal Review Group was used. This included electronic searches of the Cochrane Central Register of Controlled Trials Register (CENTRAL, The Cochrane Library, Issue 3, 2007), MEDLINE (1966 - June 2007) and EMBASE (1980 - June 2007) and CINAHL (1982 to June 2007) (all accessed via OVID) and previous reviews including cross references. SELECTION CRITERIA: Randomised controlled trials comparing feeding with formula milk versus preterm human milk in preterm or low birth weight infants. DATA COLLECTION AND ANALYSIS: The standard methods of the Cochrane Neonatal Review Group were used, with separate evaluation of trial quality and data extraction by two authors. MAIN
resultsNo eligible trials were identified. AUTHORS'
conclusionsThere are no data from randomised trials of formula milk versus maternal breast milk for feeding preterm or low birth weight infants. This may relate to a perceived difficulty of allocating an alternative feed to an infant whose mother wishes to feed with her own breast milk. Maternal breast milk remains the default choice of enteral nutrition because observational studies, and meta-analyses of trials comparing feeding with formula milk versus donor breast milk, suggest that feeding with breast milk has major non-nutrient advantages for preterm or low birth weight infants.
Indexed as
Identifiers
17943777What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.