ReviewMolecular biotechnology2008
An overview of epigenetic assays.
Review in Molecular biotechnology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Can Environmental Enrichment Modulate Epigenetic Processes in the Central Nervous System Under Adverse Environmental Conditions? A Systematic Review.Cellular and molecular neurobiology · 2024Pooled it
- Decoding cell-class specific roles of non-coding variants in human retina.Scientific reports · 2025Article
- The Role of M6A LncRNA Modification in Papillary Thyroid Cancer.International journal of molecular sciences · 2025Review
- Machine Learning Prediction of Non-Coding Variant Impact in Cell-Class-Specific Human RetinalbioRxiv : the preprint server for biology · 2025Article
- Machine Learning Prediction of Non-Coding Variant Impact in Human Retinal cis-Regulatory Elements.Translational vision science & technology · 2022Article
- ReducedInternational journal of molecular sciences · 2021Article
- The Zebrafish Model to Understand Epigenetics in Renal Diseases.International journal of molecular sciences · 2021Review
- A Comparative Overview of Epigenomic Profiling Methods.Frontiers in cell and developmental biology · 2021Review
- Article
- Sex differences in neurodevelopmental abnormalities caused by early-life anaesthesia exposure: a narrative review.British journal of anaesthesia · 2020Review
- Genomics of Particulate Matter Exposure Associated Cardiopulmonary Disease: A Narrative Review.International journal of environmental research and public health · 2019Review
- Targeting epigenetic mechanisms for chronic visceral pain: A valid approach for the development of novel therapeutics.Neurogastroenterology and motility · 2019Review
- A New Synthetic Histone Deacetylase Inhibitor, MHY2256, Induces Apoptosis and Autophagy Cell Death in Endometrial Cancer Cells via p53 Acetylation.International journal of molecular sciences · 2018Article
- Embryonic developmental temperatures modulate thermal acclimation of performance curves in tadpoles of the frog Limnodynastes peronii.PloS one · 2014Article
- DNA methylation in inflammatory genes among children with obstructive sleep apnea.American journal of respiratory and critical care medicine · 2012Article
- Epigenetic regulation of mucin genes in human cancers.Clinical epigenetics · 2011Article
- Nitric oxide: perspectives and emerging studies of a well known cytotoxin.International journal of molecular sciences · 2010Review
- Analysis of epigenetic alterations to chromatin during development.Genesis (New York, N.Y. : 2000) · 2009Review
- Chromosome-wide analysis of protein binding and modifications.Methods in molecular biology (Clifton, N.J.) · 2009Article
- Interindividual variation in epigenomic phenomena in humans.Mammalian genome : official journal of the International Mammalian Genome SocietyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A significant portion of ongoing epigenetic research involves the investigation of DNA methylation and chromatin modification patterns seen throughout many biological processes. Over the last few years, epigenetic research has undergone a gradual shift and recent studies have been directed toward a genome-wide assessment. DNA methylation and chromatin modifications are essential components of the regulation of gene activity. DNA methylation effectively down-regulates gene activity by addition of a methyl group to the five-carbon of a cytosine base. Less specifically, modification of the chromatin structure can be carried out by multiple mechanisms leading to either the upregulation or down-regulation of the associated gene. Of the many assays used to assess the effects of epigenetic modifications, chromatin immunoprecipitation (ChIP), which serves to monitor changes in chromatin structure, and bisulfite modification, which tracks changes in DNA methylation, are the two most commonly used techniques.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.