Evidence map›Paper›PMID 17943287›Full record

ReviewSeminars in immunopathology2007

B cells in glomerulonephritis: focus on lupus nephritis.

Menna R Clatworthy, Kenneth G C Smith

Abstract readReview
PubMed Publisher
In one paragraph

Review in Seminars in immunopathology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Can we cure autoimmunity?Current opinion in immunology · 2026
    Review
  2. Article
  3. Article
  4. Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  5. Fcγ Receptors in Solid Organ Transplantation.Current transplantation reports · 2016
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Neutrophils: game changers in glomerulonephritis?Trends in molecular medicine · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Menna R ClatworthyDivision of Renal Medicine, Department of Medicine and Cambridge Institute for Medical Research, University of Cambridge, Lab 5.15, Box 139 Addenbrooke's Hospital, Cambridge, CB2 2XY, UK. mrc38@cam.ac.uk
Kenneth G C Smith
University of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The production of pathogenic antibody has been traditionally viewed as the principle contribution of B cells to the pathogenesis of immune-mediated glomerulonephritis. However, it is increasingly appreciated that B cells play a much broader role in such diseases, functioning as antigen-presenting cells, regulators of T cells, dendritic cells, and macrophages and orchestrators of local lymphatic expansion. In this review, we provide an overview of basic B cell biology and consider the evidence implicating B cells in one of the archetypal immune-mediated glomerulonephritides, lupus nephritis.

Indexed as

Antibody FormationAnimalsAntibodiesB-LymphocytesDendritic CellsHumansLupus NephritisMacrophagesAntibodies

Identifiers

PMID17943287
OpenAlexW2073073241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.