ArticleGenetica2008
A comparative genomic analysis of the small heat shock proteins in Caenorhabditis elegans and briggsae.
Article in Genetica, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
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- A gap-free, telomere-to-telomere genome assembly for thebioRxiv : the preprint server for biology · 2026Article
- Revisiting the Small Heat Shock Protein Family inmicroPublication biology · 2026Article
- Article
- Understanding Diversity, Evolution, and Structure of Small Heat Shock Proteins in Annelida Through in Silico Analyses.Frontiers in physiology · 2022Article
- Transcription dynamics of heat-shock proteins (Hsps) and endosymbiont titres in response to thermal stress in whitefly,Frontiers in physiology · 2022Article
- Involvement of small heat shock proteins (sHsps) in developmental stages of fall armyworm,Heliyon · 2021Article
- Article
- The noncanonical small heat shock protein HSP-17 fromThe Journal of biological chemistry · 2020Article
- Ethylene andFrontiers in plant science · 2020Article
- Characterization and functional analysis of hsp18.3 gene in the red flour beetle, Tribolium castaneum.Insect science · 2019Article
- Characterization and expression profiles of small heat shock proteins in the marine red alga Pyropia yezoensis.Cell stress & chaperones · 2019Article
- Identification and expression analysis of multiple small heat shock protein genes in spruce budworm, Choristoneura fumiferana (L.).Cell stress & chaperones · 2018Article
- Characteristics and expression of genes encoding two small heat shock protein genes lacking introns from Chilo suppressalis.Cell stress & chaperones · 2018Article
- Transient regulation of three clustered tomato class-I small heat-shock chaperone genes by ethylene is mediated by SlMADS-RIN transcription factor.Scientific reports · 2017Article
- Identification of multiple small heat-shock protein genes in Plutella xylostella (L.) and their expression profiles in response to abiotic stresses.Cell stress & chaperones · 2015Article
- BmHSP20.8 is Localized in the Mitochondria and has a Molecular Chaperone Function In Vitro.Journal of insect science (Online) · 2015Article
- Cloning of Hsp21 gene and its expression in Chinese shrimp Fenneropenaeus chinensis in response to WSSV challenge.Journal of applied genetics · 2014Article
- Five small heat shock protein genes from Chilo suppressalis: characteristics of gene, genomic organization, structural analysis, and transcription profiles.Cell stress & chaperones · 2014Article
- Identification of novel members reveals the structural and functional divergence of lepidopteran-specific Lipoprotein_11 family.Functional & integrative genomics · 2012Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The small heat shock proteins (sHSPs) are a ubiquitous family of molecular chaperones. We have identified 18 sHSPs in the Caenorhabditis elegans genome and 20 sHSPs in the Caenorhabditis briggsae genome. Analysis of phylogenetic relationships and evolutionary dynamics of the sHSPs in these two genomes reveals a very complex pattern of evolution. The sHSPs in C. elegans and C. briggsae do not display clear orthologous relationships with other invertebrate sHSPs. But many sHSPs in C. elegans have orthologs in C. briggsae. One group of sHSPs, the HSP16s, has a very unusual evolutionary history. Although there are a number of HSP16s in both the C. elegans and C. briggsae genomes, none of the HSP16s display orthologous relationships across these two species. The HSP16s have an unusual gene pair structure and a complex evolutionary history shaped by gene duplication, gene conversion, and purifying selection. We found no evidence of recent positive selection acting on any of the sHSPs in C. elegans or in C. briggsae. There is also no evidence of functional divergence within the pairs of orthologous C. elegans and C. briggsae sHSPs. However, the evolutionary patterns do suggest that functional divergence has occurred between the sHSPs in C. elegans and C. briggsae and the sHSPs in more distantly related invertebrates.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.