Dear SIRS, the concept of "alarmins" makes a lot of sense!

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Effects of intravenous inflammasome inhibitor (NuSepin) on suppression of proinflammatory cytokines release induced by cardiopulmonary bypass in swine model: a pilot study.Scientific reports · 2024
   Article
2. Inflammatory gene expression during acute high-altitude exposure.The Journal of physiology · 2022
   Article
3. The danger from within: alarmins in arthritis.Nature reviews. Rheumatology · 2016
   Review
4. Alarmins and Antitumor Immunity.Clinical therapeutics · 2016
   Review
5. Activation of AMPK enhances neutrophil chemotaxis and bacterial killing.Molecular medicine (Cambridge, Mass.) · 2013
   Article
6. How tissue injury alarms the immune system and causes a systemic inflammatory response syndrome.Annals of intensive care · 2012
   Article
7. Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care.The journal of trauma and acute care surgery · 2012
   Review
8. Profound and persistent decrease of circulating dendritic cells is associated with ICU-acquired infection in patients with septic shock.Intensive care medicine · 2011
   Article
9. Year in review in Intensive Care Medicine 2009: II. Neurology, cardiovascular, experimental, pharmacology and sedation, communication and teaching.Intensive care medicine · 2010
   Article
10. Year in review in Intensive Care Medicine, 2008: II. Experimental, acute respiratory failure and ARDS, mechanical ventilation and endotracheal intubation.Intensive care medicine · 2009
    Review
11. Profiling genes in the ICU: are we there yet?Intensive care medicine · 2008
    Article

Corrections and comments

• Comment on
  High dose antithrombin III inhibits HMGB1 and improves endotoxin-induced acute lung injury in rats.2008

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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