Evidence map›Paper›PMID 17940588›Full record

ArticleTetrahedron2007

Oligodeoxyfluorosides: Strong Sequence Dependence of Fluorescence Emission.

James N Wilson, Jianmin Gao, Eric T Kool

Open access · greenAbstract read
In one paragraph

Article in Tetrahedron, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Luminescent Carbon Dot Mimics Assembled on DNA.Journal of the American Chemical Society · 2017
    Article
  5. Nucleic Acid-Based Nanodevices in Biological Imaging.Annual review of biochemistry · 2016
    Review
  6. Article
  7. Article
  8. Selective fluorogenic chemosensors for distinct classes of nucleases.Chembiochem : a European journal of chemical biology · 2013
    Article
  9. Article
  10. Article
  11. Multispectral labeling of antibodies with polyfluorophores on a DNA backbone and application in cellular imaging.Proceedings of the National Academy of Sciences of the United States of America · 2011
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. DNA-polyfluorophore excimers as sensitive reporters for esterases and lipases.Chemical communications (Cambridge, England) · 2010
    Article
  17. Article
  18. Polyfluorophore labels on DNA: dramatic sequence dependence of quenching.Chemistry (Weinheim an der Bergstrasse, Germany) · 2009
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

James N WilsonDepartment of Chemistry, Stanford University, Stanford CA 94305-5080.
Jianmin Gao
Eric T Kool
Stanford University · US

Funding

POLYFLUOROPHORES ASSEMBLED ON A DNA SCAFFOLDR01GM067201 · NIGMS · STANFORD UNIVERSITY · PI KOOL, ERIC T. · 2003 to 2011
$2.2M
NIGMS NIH HHS R01 GM067201
6 · The paper itself

Abstract

We describe the properties of a series of oligomeric polyfluorophores assembled on the DNA backbone. The eleven oligomers (oligodeoxyfluorosides, ODFs), 4 to 7 monomers in length, were composed of only two fluorescent monomers and a spacer in va ried sequences, and were designed to test how fluorescent nucleobases can interact electronically to yield complexity in fluorescence emission. The monomer fluorophores were deoxyribosides of pyrene and perylene, which emit light in violet and blue wavele ngths respectively. The experiments show that simple variation of sequence and spacing can dramatically change fluorescence, yielding emission maxima ranging from 380 to 557 nm and visible colors from violet to orange-red. Fluorescence lifetimes data, excitation spectra, and absorption data point to a number of multi-fluorophore electronic interactions, including pyrene-pyrene and perylene-perylene excimers, pyrene-perylene exciplexes, as well as monomer dye emissions, contributing to the final spectral outcomes. Thus, two simple fluorophores can be readily combined to give emissions over much of the visible spectrum, all requiring only a single excitation. The results demonstrate that fluorescent nucleobases in oligomeric form can act cooperatively as electronic units, and that fluorophore sequence in such oligomers is as important as fluorophore composition in determining fluorescence properties.

Identifiers

PMID17940588
PMCPMC2031844
OpenAlexW1969181691

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.