ArticleMammalian genome : official journal of the International Mammalian Genome Society1991
Meiotic mapping of murine chromosome 17: the string of loci around l(17)-2Pas.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Forward and reverse genetic approaches to behavior in the mouse.Science (New York, N.Y.) · 1994Review
- Article
- Mouse chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1992Review
- Mouse chromosome 10.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
- Mouse chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
- Mouse chromosome 13.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
- Pleiotropic action of the murine quaking locus: structure of the qkv allele.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Article
- Maps of mouse chromosome 17: first report. Committee for Mouse Chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1991Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
Abstract
We describe a genetic analysis of l(17)-2Pas, an embryonic lethal mutation on murine chromosome 17. Males transmitted the l(17)-2 allele to only 38% of their offspring, whereas females transmitted this allele at 50%. Two-point crosses revealed tight linkage between l(17)-2 and brachyury (T), and deletion mapping placed l(17)-2 outside of the hairpin-tail deletion (Thp). To map this mutation more precisely, we intercrossed hybrid mice that carry distinct alleles at many classical and DNA loci on chromosome 17 and obtained 172 animals recombinant in the T to H-2 region. Strong positive interference was observed over the 14 cM interval from T to H-2K. Thus, a single recombinant can be informative; one such recombinant places l(17)-2 distal of the molecular marker D17Leh66D. Robust genetic maps can be constructed with multilocus crosses that share anchor loci. DNA markers can be interpolated onto these maps retrospectively.
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Registered trials
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