ArticleDigestive diseases and sciences2008
Barrett's columnar-lined oesophagus: demographic and lifestyle associations and adenocarcinoma risk.
Article in Digestive diseases and sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Lifestyle, WCRF/AICR Recommendations, and Esophageal Adenocarcinoma Risk: A Systematic Review of the Literature.Nutrients · 2021Pooled it
- Lifetime risk of esophageal adenocarcinoma in patients with Barrett's esophagus.World journal of gastroenterology · 2014Pooled it
- Alcohol consumption and the neoplastic progression in Barrett's esophagus: a systematic review and meta-analysis.PloS one · 2014Pooled it
- Article
- Predictors of dysplastic and neoplastic progression of Barrett’s esophagusCanadian journal of surgery. Journal canadien de chirurgie · 2019Article
- Challenges in Endoscopic Therapy of Dysplastic Barrett's Esophagus.Current treatment options in gastroenterology · 2019Review
- Risk stratification for malignant progression in Barrett's esophagus: Gender, age, duration and year of surveillance.World journal of gastroenterology · 2016Article
- Barrett's oesophagus: Evidence from the current meta-analyses.World journal of gastrointestinal pathophysiology · 2014Review
- Risk of malignant progression in Barrett's esophagus patients: results from a large population-based study.Journal of the National Cancer Institute · 2011Article
- Barrett's esophagus: where do we stand?Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2009Article
- Alcohol consumption is associated with an increased risk of erosive esophagitis and Barrett's epithelium in Japanese men.BMC gastroenterology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesLifestyle and demographic risk factors for the development of oesophageal adenocarcinoma developing from columnar-lined oesophagus are not well defined.
methodsDemographic and lifestyle factors, endoscopy and histology reports were extracted from 1,761 subjects from seven UK centres. The associations of columnar-lined oesophagus with demographic and lifestyle factors and the development of adenocarcinoma were examined.
results5.5% of patients had prevalent adenocarcinoma (more common in males, older patients, patients diagnosed earlier in the cohort and current or recent smokers). Adenocarcinoma incidence was 23 patients in 3,912 years or 0.59% per annum. Only increased age at diagnosis correlated with an increased risk of incident adenocarcinoma. There was no association with obesity or alcohol history.
conclusionsOesophageal adenocarcinoma occurs more commonly in older patients and is more frequent in males than females. Once columnar-lined oesophagus had been diagnosed, there were no other demographic or lifestyle factors which were predictive of the development of incident adenocarcinoma in this cohort.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.