ReviewSeminars in immunopathology2007
Leukocytes in glomerular injury.
Review in Seminars in immunopathology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 43 citations in OpenAlex.
- Twist1 in podocytes ameliorates podocyte injury and proteinuria by limiting CCL2-dependent macrophage infiltration.JCI insight · 2021Article
- GPRC5b Modulates Inflammatory Response in Glomerular DiseasesJournal of the American Society of Nephrology : JASN · 2019Article
- Advanced glycation end products induce the apoptosis of and inflammation in mouse podocytes through CXCL9-mediated JAK2/STAT3 pathway activation.International journal of molecular medicine · 2017Article
- P-Selectin preserves immune tolerance in mice and is reduced in human cutaneous lupus.Scientific reports · 2017Article
- Molecular studies of lupus nephritis kidneys.Immunologic research · 2015Review
- Dendritic Cells and Macrophages: Sentinels in the Kidney.Clinical journal of the American Society of Nephrology : CJASN · 2015Review
- Inflammation-Induced IL-6 Functions as a Natural Brake on Macrophages and Limits GN.Journal of the American Society of Nephrology : JASN · 2015Article
- Endothelin and the glomerulus in chronic kidney disease.Seminars in nephrology · 2015Review
- Demethylzeylasteral (T-96) Treatment Ameliorates Mice Lupus Nephritis Accompanied by Inhibiting Activation of NF-κB Pathway.PloS one · 2015Article
- Structure and function of renal macrophages and dendritic cells from lupus-prone mice.Arthritis & rheumatology (Hoboken, N.J.) · 2014Article
- Stem cells: potential and challenges for kidney repair.American journal of physiology. Renal physiology · 2014Review
- Cgnz1 allele confers kidney resistance to damage preventing progression of immune complex-mediated acute lupus glomerulonephritis.The Journal of experimental medicine · 2013Article
- The renal mononuclear phagocytic system.Journal of the American Society of Nephrology : JASN · 2012Review
- Platelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway.The American journal of pathology · 2010Article
- Neutrophils: game changers in glomerulonephritis?Trends in molecular medicine · 2010Review
- Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells.Arthritis research & therapy · 2009Article
- Immune system in renal injury and repair: burning the candle from both ends?Pharmacological research · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leukocytes of the innate immune system play a central protective role in immune defense to pathogens but may also mediate injurious inflammatory responses resulting in tissue injury. These leukocytes provide the first rapid cellular defense mechanisms through a limited repertoire of rapid pre-programmed responses, but they are also involved in chronic inflammation and tissue repair. They are directed to sites of pathogen challenge and inflammation by a variety of mechanisms and are activated in response to both exogenous and endogenous stimuli. They do not show the capacity of self-non-self discrimination and memory, which are defining characteristics of the adaptive immune system, although macrophages in particular may show some capacity for differentiation of their effector responses. However, they do play an integral role in adaptive immune responses by their capacity to present antigen, modify T-cell development, and function as effectors of adaptive cell-mediated immunity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.