ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2008
Does sequence polymorphism of FLC paralogues underlie flowering time QTL in Brassica oleracea?
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 64 citations in OpenAlex.
- Molecular Evaluation of the Effects ofGenes · 2024Article
- Genetic dissection of morphological variation between cauliflower and a rapid cycling Brassica oleracea line.G3 (Bethesda, Md.) · 2023Article
- Upregulation of tandem duplicated BoFLC1 genes is associated with the non-flowering trait in Brassica oleracea var. capitata.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Article
- Non-vernalization requirement in Chinese kale caused by loss of BoFLC and low expressions of its paralogs.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Genome sequencing sheds light on the contribution of structural variants to Brassica oleracea diversification.BMC biology · 2021Article
- Total FLC transcript dynamics from divergent paralogue expression explains flowering diversity in Brassica napus.The New phytologist · 2021Article
- Comparative Transcriptome Analysis of Early- and Late-Bolting Traits in Chinese Cabbage (Frontiers in genetics · 2021Article
- From landrace to modern hybrid broccoli: the genomic and morphological domestication syndrome within a diverseHorticulture research · 2020Article
- The vernalisation regulator FLOWERING LOCUS C is differentially expressed in biennial and annual Brassica napus.Scientific reports · 2019Article
- Molecular markers based on sequence variation in BoFLC1.C9 for characterizing early- and late-flowering cabbage genotypes.BMC genetics · 2019Article
- Complex Horticultural Quality Traits in Broccoli Are Illuminated by Evaluation of the Immortal BolTBDH Mapping Population.Frontiers in plant science · 2019Article
- Translating Flowering Time From Arabidopsis thaliana to Brassicaceae and Asteraceae Crop Species.Plants (Basel, Switzerland) · 2018Review
- Genome-Wide Identification of Flowering-Time Genes inInternational journal of molecular sciences · 2018Article
- Subtropical adaptation of a temperate plant (Brassica oleracea var. italica) utilizes non-vernalization-responsive QTLs.Scientific reports · 2018Article
- The production and characterization of aBreeding science · 2018Article
- Genome-Based Prediction of Time to Curd Induction in Cauliflower.Frontiers in plant science · 2018Article
- Molecular mapping of QTL alleles of Brassica oleracea affecting days to flowering and photosensitivity in spring Brassica napus.PloS one · 2018Article
- Flowering Time Gene Variation inFrontiers in plant science · 2017Article
- Nucleotide polymorphism affecting FLC expression underpins heading date variation in horticultural brassicas.The Plant journal : for cell and molecular biology · 2016Article
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous locations of flowering time (FT) QTL in several Brassica species, coupled with Arabidopsis synteny, suggest that orthologues of the genes FLC, FY or CONSTANS might be the candidates. We focused on FLC, and cloned paralogous copies in Brassica oleracea, obtained their genomic DNA sequences, and confirmed their locations relative to those of known FT-QTL by genetical mapping. They varied in total length mainly due to the variable size of the first and last introns. A high level of identity was observed among Brassica FLC genes at the amino acid level but non-synonymous differences were present. Comparative analysis of the promoter and intragenic regions of BoFLC paralogues with Arabidopsis FLC revealed extensive differences in overall structure and organisation but showed high conservation within those segments known to be essential in regulating FLC expression. Four B. oleracea FLC copies (BoFLC1, BoFLC3, BoFLC4 and BoFLC5) were located to their respective linkage groups based on allelic sequence variation in lines from a doubled haploid population. All except BoFLC4 were within the confidence intervals of known FT-QTL. Sequence data indicated that relevant non-synonymous polymorphisms were present between parents A12DHd and GDDH33 for BoFLC genes. However, BoFLC alleles segregated independently of FT in backcrosses while the study provided evidence that BoFLC4 and BoFLC5 contain premature stop codons and so could not contribute to flowering time variation. Therefore, there is strong evidence against any of the 4 BoFLC being FT-QTL candidates in this population.
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