Evidence map›Paper›PMID 17936890›Full record

ArticleThe Journal of allergy and clinical immunology2008

IL-1 blockade in Schnitzler syndrome: ex vivo findings correlate with clinical remission.

John G Ryan, Heleen D de Koning, Lisa A Beck, Matthew G Booty, Daniel L Kastner, Anna Simon

Registry-linked trialAbstract readCase ReportsLetter
PubMed Publisher
In one paragraph

Article in The Journal of allergy and clinical immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01276522 (Efficacy and Safety of Canakinumab in Schnitzler Syndrome), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01276522 phase2completednot on this mapstarted 2011, after this paper: background citation

Efficacy and Safety of Canakinumab in Schnitzler Syndrome

TypeinterventionalSponsorRadboud University Medical CenterRan2011 to 2011Enrolled8ConditionsSchnitzler SyndromeArmsCanakinumab
3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Schnitzler syndrome.Dermatologie (Heidelberg, Germany) · 2025
    Review
  2. Review
  3. Review
  4. Article
  5. [Clinical symptoms of autoinflammatory diseases].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2020
    Review
  6. Article
  7. Review
  8. [Schnitzler syndrome].Zeitschrift fur Rheumatologie · 2019
    Article
  9. [Schnitzler syndrome].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2018
    Article
  10. Article
  11. Review
  12. Schnitzler Syndrome: a Review.Current rheumatology reports · 2017
    Review
  13. Review
  14. Article
  15. Schnitzler's syndrome: lessons from 281 cases.Clinical and translational allergy · 2014
    Review
  16. Review
  17. Article
  18. Review
  19. [Schnitzler syndrome].Zeitschrift fur Rheumatologie · 2012
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

John G Ryan
Heleen D de Koning
Lisa A Beck
Matthew G Booty
Daniel L Kastner
Anna Simon

Funding

Clinical Support Services for the NIAMS Intramural Research ProgramZ01AR041180 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KASTNER, DANIEL · 2008 to 2008
$3.4M
GENETICS OF THE DOMINANTLY INHERITED PERIODIC FEVER SYNDROMESZ01AR041123 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KASTNER, DANIEL L · 1999 to 2008
$2.8M
Intramural NIH HHS
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antirheumatic AgentsFemaleHumansInterleukin-1Interleukin 1 Receptor Antagonist ProteinMiddle AgedSchnitzler SyndromeTreatment OutcomeAntirheumatic AgentsInterleukin-1Interleukin 1 Receptor Antagonist Protein

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.