Evidence map›Paper›PMID 17934888›Full record

ArticlePediatric nephrology (Berlin, Germany)2008

Linear growth in pediatric hemodialysis patients.

Gregory Gorman, Diane Frankenfield, Barbara Fivush, Alicia Neu

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00943995 (TIW Growth Hormone Therapy in Children on Hemodialysis), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00943995 phase3completednot on this mapstarted 2010, after this paper: background citation

TIW Growth Hormone Therapy in Children on Hemodialysis

TypeinterventionalSponsorNationwide Children's HospitalRan2010 to 2012Enrolled3ConditionsKidney Failure, Chronic, Renal DialysisArmssomatropin
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Geographic determinants of access to pediatric deceased donor kidney transplantation.Journal of the American Society of Nephrology : JASN · 2014
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Gregory GormanDepartment of Pediatrics, National Naval Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20889, USA. ggorman@usuhs.mil
Diane Frankenfield
Barbara Fivush
Alicia Neu
Johns Hopkins University · USNaval Medical Research Command · USThe Centers · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth is an important outcome in pediatric kidney disease. We aimed to identify factors associated with growth in pediatric hemodialysis (HD) patients. Height standard deviation scores (Ht SDS) of pediatric HD patients with consecutive height measurements in the ESRD Clinical Performance Measures Project were calculated. Multiple linear regression determined the effect of factors on Ht SDS change/year. Four hundred and seven patients were included. Median age was 15.2 years (interquartile range 13.2-16.5 years); 44% were girls, and 27% were black. Of patients observed, 66% had growth hormone (GH) data, and of those, 29% were prescribed GH. Mean change in Ht SDS/year was -0.10+/-0.71. After adjustment, decreasing Ht SDS was associated with younger age (-0.2/year for <13 vs. >or=13 years; p<0.0001), longer duration on dialysis (-0.03/year for >or=6 months vs. <6 months; p<0.01), and higher normalized protein catabolic rate (nPCR) (-0.02/year per 0.1; p<0.05). Improved growth was seen in girls (0.10/year; p<0.01) and in those with lower Ht SDS (0.03/year per 0.5 decrease; p<0.001). Hemoglobin, GH use, and adequacy were associated with neither positive nor negative changes in Ht SDS. Growth retardation while on HD was most pronounced in patients who were young, male, had longer durations on HD, had higher nPCR, and had higher baseline Ht SDS.

Indexed as

GrowthRenal DialysisAdolescentBody HeightChildFemaleGrowth HormoneHumansKidney Failure, ChronicLinear ModelsMaleGrowth Hormone

Identifiers

PMID17934888
OpenAlexW2146099524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.