Evidence map›Paper›PMID 17934684›Full record

ArticleSocial psychiatry and psychiatric epidemiology2007

Remission of maternal depression and child symptoms among single mothers: a STAR*D-Child report.

Ardesheer Talati, Priya J Wickramaratne, Daniel J Pilowsky, Jonathan E Alpert, Gabriele Cerda, Judy Garber, Carroll W Hughes, Cheryl A King, Erin Malloy, A Bela Sood and 4 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Citalopram versus other anti-depressive agents for depression.The Cochrane database of systematic reviews · 2012
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Screening parents during child evaluations: exploring parent and child psychopathology in the same clinic.Journal of the American Academy of Child and Adolescent Psychiatry · 2011
    Article
  7. Secondhand smoke exposure and mental health among children and adolescents.Archives of pediatrics & adolescent medicine · 2011
    Article
  8. Article
  9. The persistence of maternal distress and symptoms of distress in adult offspring.Social psychiatry and psychiatric epidemiology · 2009
    Article
  10. Article
  11. Depression.Annals of epidemiology · 2009
    Review
  12. Article
  13. Article
  14. Continuity of paternal social support and depressive symptoms among new mothers.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2008
    Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Ardesheer TalatiDept. of Psychiatry, Columbia University, 1051 Riverside Drive, Unit 24, New York, NY 10032, USA. at2071@columbia.edu
Priya J Wickramaratne
Daniel J Pilowsky
Jonathan E Alpert
Gabriele Cerda
Judy Garber
Carroll W Hughes
Cheryl A King
Erin Malloy
A Bela Sood
Helen Verdeli
Madhukar H Trivedi
A John Rush
Myrna M Weissman
Columbia University · USThe University of Texas Southwestern Medical Center · USMassachusetts General Hospital · USUniversity of California, San Diego · USUniversity of Michigan–Ann Arbor · USUniversity of North Carolina at Chapel Hill · USVanderbilt University · USVirginia Commonwealth University · US

Funding

Children of Depressed Mothers: a STAR*D Ancillary StudyR01MH063852 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WEISSMAN, MYRNA M · 2001 to 2005
$5.1M
Risk and Prevention of Depression in YouthK02MH066249 · NIMH · VANDERBILT UNIVERSITY · PI GARBER, JUDY · 2003 to 2007
$604k
TREATMENT RESISTANT DEPRESSION-278990003N01MH090003 · NIMH · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · 1999 to 2003
–
NIMH NIH HHS K02 MH066249NIMH NIH HHS K02 MH66249NIMH NIH HHS N01 MH090003NIMH NIH HHS R01 MH063852NIMH NIH HHS R01MH063852
6 · The paper itself

Abstract

objectiveOffspring of depressed parents are at increased risk for depressive and other disorders. We recently found that when depressed mothers reached full remission over 3 months of treatment, a significant improvement in the children's disorders occurred. Since only a third of the mothers remitted, factors related to maternal remission rates, and thereby child outcomes, were important. This report examined the relationship of the presence of a father in the household to maternal depression remission and child outcomes.

methodMaternal depression was measured using the 17-item Hamilton Rating Scale for Depression (HRSD(17)); social functioning was assessed using the Social Adjustment Scale-Self Report (SAS-SR). Children (age 7-17) were assessed independently, blind to maternal outcome, using the Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS-PL) and the Child Global Assessment Scale (C-GAS).

resultsSingle mothers (n = 50), as compared to those in two-parent households (n = 61), were more likely to discontinue treatment (31% vs. 16%, P = 0.04), and less likely to remit if they remained in treatment (20% vs. 43%, P = 0.013). These differences remained significant after adjusting for socioeconomic status and potential confounders, but were partially explained by the mother's pre-treatment social functioning. The reduction in child diagnoses following maternal remission was greater in two-parent than in single-parent households, although a formal test of interaction between the odds ratios was not significant.

conclusionSingle depressed mothers are more likely to drop out of treatment, and less likely to reach remission if they stay in treatment. This high-risk group requires vigorous treatment approaches.

Indexed as

Major Depressive DisorderAdolescentAdultChildChild of Impaired ParentsDemographyFemaleHumansMaleMothersPaternal BehaviorRemission, SpontaneousSingle Parent

Identifiers

PMID17934684
PMCPMC2994601
OpenAlexW2072113873

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.