Evidence map›Paper›PMID 17934078›Full record

ReviewClinical microbiology reviews2007

Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection.

Vincent C C Cheng, Susanna K P Lau, Patrick C Y Woo, Kwok Yung Yuen

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 530 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
530citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04642326 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Prospective, Parallel, Multicenter Randomized Controlled Study Investigating the Effects of UVC Beam and Laser Beam Therapy According to Standard Therapy in Patients With Covid-19 Diagnosis

TypeinterventionalSponsorRD Global Araştirma Geliştirme Sağlik Ilaç Inşaat Yatirimlari A.Ş.Ran2020 to 2021Enrolled50ConditionsCovid19ArmsTest Group: experimental - UVC Therapy applied
NCT05216471 unknown statusnot on this mapstarted 2021, after this paper: background citation

Diagnostic Accuracy of Chest X-ray in Coronavirus Disease 2019

TypeobservationalSponsorAssiut UniversityRan2021 to 2023Enrolled150ConditionsCoronavirus Disease 2019Armschest X-ray
3 · Its place in the literature

Who cites it

530 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  12. One health (Amsterdam, Netherlands) · 2025
    Article
  13. Stroke, infections, and New Mechanisms: a Narrative Review.Current neurology and neuroscience reports · 2025
    Review
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470 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vincent C C ChengState Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Susanna K P Lau
Patrick C Y Woo
Kwok Yung Yuen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Before the emergence of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) in 2003, only 12 other animal or human coronaviruses were known. The discovery of this virus was soon followed by the discovery of the civet and bat SARS-CoV and the human coronaviruses NL63 and HKU1. Surveillance of coronaviruses in many animal species has increased the number on the list of coronaviruses to at least 36. The explosive nature of the first SARS epidemic, the high mortality, its transient reemergence a year later, and economic disruptions led to a rush on research of the epidemiological, clinical, pathological, immunological, virological, and other basic scientific aspects of the virus and the disease. This research resulted in over 4,000 publications, only some of the most representative works of which could be reviewed in this article. The marked increase in the understanding of the virus and the disease within such a short time has allowed the development of diagnostic tests, animal models, antivirals, vaccines, and epidemiological and infection control measures, which could prove to be useful in randomized control trials if SARS should return. The findings that horseshoe bats are the natural reservoir for SARS-CoV-like virus and that civets are the amplification host highlight the importance of wildlife and biosecurity in farms and wet markets, which can serve as the source and amplification centers for emerging infections.

Indexed as

AnimalsCatsCommunicable Diseases, EmergingDisease Models, AnimalDisease OutbreaksGuinea PigsHumansInfection ControlSevere Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirus

Identifiers

PMID17934078
PMCPMC2176051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.