SynthesisCanadian family physician Medecin de famille canadien2007
Non-cancer health effects of pesticides: systematic review and implications for family doctors.
Synthesis in Canadian family physician Medecin de famille canadien, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 193 citations in OpenAlex.
- Impact of organic foods on chronic diseases and health perception: a systematic review of the evidence.European journal of clinical nutrition · 2025Pooled it
- Community Health Impacts of Pesticide Exposure: Pathways, Vulnerable Populations, and Public Health Responses.International journal of environmental research and public health · 2026Review
- Review
- Design, Synthesis, and Aphicidal Activity of Novel Insect Neuropeptide Kinin Receptor Antagonists, Targeting the SerJournal of agricultural and food chemistry · 2025Article
- Review
- Pesticide exposure and acute health problems among pesticide processing industry workers in Ethiopia.Toxicology reports · 2025Article
- A predictive framework using advanced machine learning approaches for measuring and analyzing the impact of synthetic agrochemicals on human health.Scientific reports · 2025Article
- Lived experiences of farmworkers from five U. S. states during the COVID-19 pandemic.Frontiers in public health · 2025Article
- Liquid Bioformulation: A Trending Approach Towards Achieving Sustainable Agriculture.Molecular biotechnology · 2024Review
- Pesticides impacts on human health and the environment with their mechanisms of action and possible countermeasures.Heliyon · 2024Review
- Investigating the levels of organochlorine pesticides in human milk at three lactational stages: an intensive Ghanaian study.Environmental monitoring and assessment · 2024Article
- Redox mechanisms of environmental toxicants on male reproductive function.Frontiers in cell and developmental biology · 2024Review
- Analyzing Factors Affecting Farmers' Safe Pesticide Handling Practices in Southwest of Ethiopia: Implications for Policy.Environmental health insights · 2024Article
- Degradation of Pesticide Residues in Water, Soil, and Food Products via Cold Plasma Technology.Foods (Basel, Switzerland) · 2023Review
- Review
- Environmental toxicants and health adversities: A review on interventions of phytochemicals.Journal of public health research · 2023Article
- Integrating Environmental Data with Medical Data in a Records-Linkage System to Explore Groundwater Nitrogen Levels and Child Health Outcomes.International journal of environmental research and public health · 2023Article
- Environmental and Health Risks of Pesticide Use in Ethiopia.Journal of health & pollution · 2021Review
- Evaluation of pesticide residues in fruits and vegetables from the Aegean region of Turkey and assessment of risk to consumers.Environmental science and pollution research international · 2021Article
- Broad host range bacteriophages found in rhizosphere soil of a healthy tomato plant in Bulgaria.Heliyon · 2021Article
Corrections and comments
- Commented on byFriend or foe.2007
- Commented on by
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate whether there are associations between exposure to pesticides and 4 chronic non-cancer health effects: dermatologic, neurologic, reproductive, and genotoxic effects. DATA SOURCES: We searched PreMedline, MEDLINE, and LILACS using the key word pesticide combined with the term for the specific health effect being searched. Reviewers scanned the references of all articles for additional relevant studies. STUDY SELECTION: Studies since 1992 were assessed using structured inclusion and quality-of-methods criteria. Studies scoring <4 on a 7-point global methodologic quality scale were excluded. In total, 124 studies were included. These studies had a mean quality score of 4.88 out of 7. SYNTHESIS: Strong evidence of association with pesticide exposure was found for all neurologic outcomes, genotoxicity, and 4 of 6 reproductive effects: birth defects, fetal death, altered growth, and other outcomes. Exposure to pesticides generally doubled the level of genetic damage as measured by chromosome aberrations in lymphocytes. Only a few high-quality studies focused on the dermatologic effects of pesticides. In some of these studies, rates of dermatitis were higher among those who had had high exposure to pesticides on the job.
conclusionEvidence from research on humans consistently points to positive associations between pesticide exposure and 3 of the 4 non-cancer health outcomes studied. Physicians have a dual role in educating individual patients about the risks of exposure and in reducing exposure in the community by advocating for restrictions on use of pesticides.
Indexed as
Identifiers
17934035PMC2231436W2112799083What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.