ArticleHeart (British Cardiac Society)2007
Gender differences in management and outcomes in patients with acute coronary syndromes: results on 20,290 patients from the AMIS Plus Registry.
Article in Heart (British Cardiac Society), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 1 of them a synthesis that pooled it.
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Who cites it
85 citing papers in PubMed, 1 synthesis or guideline pooled it, 263 citations in OpenAlex.
- Gender Differences in Treatment Delays, Management and Mortality among Patients with Acute Coronary Syndrome: A Systematic Review and Meta-analysis.Current cardiology reviews · 2023Pooled it
- Sex Differences in Clinical Characteristics and Outcomes After Myocardial Infarction With Low Ejection Fraction: Insights From PARADISE-MI.Journal of the American Heart Association · 2023Trial
- Presenting Symptoms in Patients Undergoing Coronary Artery Disease Evaluation: Association With Noninvasive Test Results and Clinical Outcomes in the PROMISE Trial.Circulation. Cardiovascular quality and outcomes · 2022Trial
- The efficacy of ticagrelor is maintained in women with acute coronary syndromes participating in the prospective, randomized, PLATelet inhibition and patient Outcomes (PLATO) trial.European heart journal · 2014Trial
- Trial
- Sex differences in the presentation and management of acute coronary syndrome patients: Insights from the FORCE-ACS registry.International journal of cardiology. Heart & vasculature · 2026Article
- Gender-based differences among ST-elevation myocardial infarction patients in Egypt: secondary analysis from the ACCA-EAPCI ESC-STEMI registry.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025Article
- Drosophila melanogaster as a model organism to investigate sex specific differences.Scientific reports · 2025Article
- Emerging opportunities to target inflammation: myocardial infarction and type 2 diabetes.Cardiovascular research · 2024Review
- Sex differences in outcomes after acute coronary syndrome vary with age: a New Zealand national study.European heart journal. Acute cardiovascular care · 2024Article
- The Impact of Sex on Cardiogenic Shock Outcomes Following ST Elevation Myocardial Infarction.Journal of clinical medicine · 2023Article
- The impact of end-stage kidney disease on mortality in patients after acute myocardial infarction: A nationwide study.Journal of the Chinese Medical Association : JCMA · 2023Article
- Gender disparities in prevalence by diagnostic criteria, treatment and mortality of newly diagnosed acute myocardial infarction in Korean adults.Scientific reports · 2023Article
- Patterns, Predictors, and Intercenter Variability in Empiric Gram-Negative Antibiotic Use Across 928 United States Hospitals.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- A bibliometric analysis of acute myocardial infarction in women from 2000 to 2022.Frontiers in cardiovascular medicine · 2023Article
- Discrepancies in post-ST-elevation myocardial infarction care in women compared with men: evaluating for implicit bias-a single-centre study.Irish journal of medical science · 2022Article
- Cardiac rehabilitation - The answer for the second chance.American heart journal plus : cardiology research and practice · 2022Review
- Ultra-highly sensitive cardiac troponin I: Age and sex differences in healthy individuals.American heart journal plus : cardiology research and practice · 2022Article
- Gender differences in acute myocardial infarction-A nationwide German real-life analysis from 2014 to 2017.Clinical cardiology · 2021Article
- Recorded but not revealed: exploring the relationship between sex and gender, country income level, and COVID-19.The Lancet. Global health · 2021Article
25 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGender differences in management and outcomes have been reported in acute coronary syndrome (ACS).
objectivesTo assess such gender differences in a Swiss national registry.
methods20 290 patients with ACS enrolled in the AMIS Plus Registry from January 1997 to March 2006 by 68 hospitals were included in a prospective observational study. Data on patients' characteristics, diagnoses, procedures, complications and outcomes were recorded. Odds ratios (ORs) of in-hospital mortality were calculated using logistic regression models.
results5633 (28%) patients were female and 14 657 (72%) male. Female patients were older than men (mean (SD) age 70.9 (12.1) vs 63.4 (12.9) years; p<0.001), had more comorbidities and came to hospital later. They underwent percutaneous coronary intervention (PCI) less frequently (OR = 0.65; 95% CI 0.61 to 0.69) and their unadjusted in-hospital mortality was higher overall (10.7% vs 6.3%; p<0.001) and in those who underwent PCI (3.0% vs 4.2%; p = 0.018). Mortality differences between women and men disappeared after adjustments for other predictors (adjusted OR (aOR) for women vs men: 1.09; 95% CI 0.95 to 1.25), except in women aged 51-60 years (aOR = 1.78; 95% CI 1.04 to 3.04). However, even after adjustments, female gender remained significantly associated with a lower probability of undergoing PCI (OR = 0.70; 95% CI 0.64 to 0.76).
conclusionsThe analysis showed gender differences in baseline characteristics and in the rate of PCI in patients admitted for ACS in Swiss hospitals between 1997 and 2006. Reasons for the significant underuse of PCI in women, and a slightly higher in-hospital mortality in the 51-60 year age group, need to be investigated further.
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