ArticleNeuroradiology2008
Comparative in vitro study of five mechanical embolectomy systems: effectiveness of clot removal and risk of distal embolization.
Article in Neuroradiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 60 citations in OpenAlex.
- In vitro models for the experimental evaluation of mechanical thrombectomy devices in acute ischemic stroke.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2023Review
- Novel Blood Clot Retriever for Ischemic Stroke.Micromachines · 2021Article
- Two cases of successful recanalization for acute cerebral artery embolism during perioperative period of radiofrequency ablation for atrial fibrillation.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2020Article
- Preclinical Evaluation of the NeVaTM Stent Retriever: Safety and Efficacy in the Swine Thrombectomy Model.Interventional neurology · 2018Article
- Solitaire Stent in the Treatment of Acute Ischemic Stroke with Large Cerebral Artery Occlusion.Translational neuroscience · 2017Article
- The quest for arterial recanalization in acute ischemic stroke-the past, present and the future.Journal of clinical medicine research · 2013Article
- The phenox clot retriever as part of a multimodal mechanical thrombectomy approach in acute ischemic stroke: single center experience in 56 patients.TheScientificWorldJournal · 2012Article
- Safety and efficacy of the Aperio thrombectomy device when compared to the Solitaire AB/FR and the Revive devices in a pulsatile flow system.American journal of cardiovascular disease · 2012Article
- Advances in stroke therapy.Drug delivery and translational research · 2011Article
- Mechanical thrombectomy in acute ischemic stroke: catch device.AJNR. American journal of neuroradiology · 2011Article
- Mechanical characterization of thromboemboli in acute ischemic stroke and laboratory embolus analogs.AJNR. American journal of neuroradiology · 2011Article
- A novel mechanical thrombectomy device for retrieval of intravascular thrombus.Cardiovascular and interventional radiology · 2011Article
- Endovascular stroke treatment today.AJNR. American journal of neuroradiology · 2011Review
- Comparison of the Effectiveness of Three Methods of Recanalization in a Model of the Middle Cerebral Artery: Thrombus Aspiration via a 4F Catheter, Thrombus Aspiration via the GP Thromboaspiration Device, and Mechanical Thrombectomy Using the Solitaire Thrombectomy Device.Stroke research and treatment · 2011Article
- Intra-arterial treatment methods in acute stroke therapy.Frontiers in neurology · 2011Article
- Autopsy findings after intracranial thrombectomy for acute ischemic stroke: a clinicopathologic study of 5 patients.Stroke · 2010Article
- In vivo evaluation of the Phenox CRC mechanical thrombectomy device in a swine model of acute vessel occlusion.AJNR. American journal of neuroradiology · 2010Article
- Containing a Clot in the Mid-Basilar Artery Using a Self-Expandable Stent to Prevent Distal Clot Migration during Intra-Arterial Thrombolysis. A Case Report.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2009Article
- Endovascular approaches to acute stroke, part 1: Drugs, devices, and data.AJNR. American journal of neuroradiology · 2009Review
- Acute stroke therapy 1981-2009.Klinische Neuroradiologie · 2009Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe report an in vitro study comparing the effectiveness of clot removal and clot fragmentation of five embolectomy systems.
methodsA flow model was embolized with fresh and old thrombi, occluding an inner diameter of 2-5 mm simulating internal carotid artery (ICA), basilar artery (BA) and middle cerebral artery (MCA) branch occlusion. Embolectomy was performed using five retrieval systems: CATCH (Balt), Merci retriever (Concentric), InTime and Attracter (Boston Scientific), and the Phenox Clot Retriever (Phenox). Clot removal and evidence and type of thrombus fragmentation and distal embolization were recorded.
resultsThere were no observable differences attributable to thrombus age. The Merci, CATCH and Phenox Clot Retriever were equally able to mobilize and remove thrombi with the exception of one particularly firm clot. There were marked differences in terms of thrombus fragmentation and distal embolization. All devices produced micro- and macrofragments during penetration and retrieval. The Phenox Clot Retriever was able to filter fragments. The InTime and Attracter devices failed to retrieve thrombi in this model and achieved partial removal at best with a tendency towards thrombus displacement and fragmentation.
conclusionWithin limits, the experimental setup was appropriate for generating occlusions of diameter 2-5 mm of various lengths, simulating ICA, BA and MCA thromboembolism. In this model, thrombus mobilization appeared to be less dependent upon the individual design of the retrieval system than on thrombus fragmentation. The ability to prevent distal embolization is, however, strongly dependent on the ability of a thrombectomy device to capture fragments that are generated during removal of the device.
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