Trial reportInternational urogynecology journal and pelvic floor dysfunction2008
Short-term results of bilateral S2-S4 sacral neuromodulation for the treatment of refractory interstitial cystitis, painful bladder syndrome, and chronic pelvic pain.
Trial report in International urogynecology journal and pelvic floor dysfunction, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Sacral neuromodulation treating chronic pelvic pain: a meta-analysis and systematic review of the literature.International urogynecology journal · 2019Pooled it
- Sacral Neuromodulation for Refractory Bladder Pain Syndrome/Interstitial Cystitis: a Global Systematic Review and Meta-analysis.Scientific reports · 2017Pooled it
- Sacral nerve modulation in the treatment of chronic pelvic pain.International journal of colorectal disease · 2012Trial
- Spinal Cord Stimulation for Intractable Visceral Pain Originating from the Pelvic and Abdominal Region: A Narrative Review on a Possible New Indication for Patients with Therapy-Resistant Pain.Journal of pain research · 2024Review
- Neuromodulation for Management of Chronic Pelvic Pain: A Comprehensive Review.Pain and therapy · 2022Review
- Neuromodulation in Chronic Pelvic Pain: A Narrative Review.Pain and therapy · 2022Review
- Variable- versus constant-frequency sacral neuromodulation in black-zone overactive bladder patients: a study protocol for a multicenter, prospective, randomized, blind, self-controlled trial.Translational andrology and urology · 2021Article
- Neuromodulation for Pelvic and Urogenital Pain.Brain sciences · 2018Review
- Painful bladder syndrome: an update and review of current management strategies.Current urology reports · 2014Review
- Interstitial cystitis/bladder pain syndrome: diagnosis and management.International urogynecology journal · 2013Review
- Neuromodulation in male chronic pelvic pain syndrome: rationale and practice.World journal of urology · 2013Review
- Battery explantation after sacral neuromodulation in the Medicare population.Neurourology and urodynamics · 2013Article
- [Chronic pelvic pain syndrome: neurostimulation, neuromodulation and acupuncture].Der Urologe. Ausg. A · 2012Article
- Efficacy of sacral neuromodulation in treating chronic pain related to painful bladder syndrome/interstitial cystitis in adults.Journal of anaesthesiology, clinical pharmacology · 2012Article
- Sacral neuromodulation for lower urinary tract dysfunction.World journal of urology · 2012Review
- Pelvic pain in urogynecology. Part II: treatment options in patients with lower urinary tract symptoms.International urogynecology journal · 2012Review
- The use of radiotherapy in the management of follicular cystitis refractory to conservative and surgical management.Rare tumors · 2012Article
- A new technique for inferior hypogastric plexus block: a coccygeal transverse approach -a case report-.The Korean journal of pain · 2012Article
- Minimum 6-year outcomes for interstitial cystitis treated with sacral neuromodulation.International urogynecology journal · 2011Article
- Selection of ideal candidates for neuromodulation in refractory overactive bladder.Current urology reports · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We evaluated the efficacy of bilateral caudal epidural sacral neuromodulation for the treatment of refractory chronic pelvic pain (CPP), painful bladder syndrome, and interstitial cystitis (IC). Thirty consecutive patients (21 female, 9 male) with severe refractory symptoms underwent bilateral S2-S4 sacral neuromodulation for CPP/IC. Patients were evaluated with the O'Leary IC symptom and problem index (ICSI, ICPI), the short form of the Urogenital Distress Inventory (UDI-6), and the RAND 36-item health survey (SF-36) preoperatively and 6 months postoperatively. The mean and minimum follow-up were 15 and 6 months, respectively. Of the 30 patients, 23 (77%) had a successful trial stimulation and were permanently implanted. Among these patients, the ICSI and ICPI scores improved by 35 (p = 0.005) and 38% (p = 0.007), respectively. The pain score improved by 40% (p = 0.04) and the UDI-6 score by 26% (p = 0.05). On average, patients reported a 42% improvement in their symptoms. SF-36 scores did not improve significantly. In refractory patients, bilateral caudal epidural sacral neuromodulation is another possible mode of treatment, which appears to improve both pelvic pain and voiding symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.