ArticleScandinavian journal of primary health care2007
Electronic pillboxes (MEMS) to assess the relationship between medication adherence and blood pressure control in primary care.
Article in Scandinavian journal of primary health care, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Mobile Apps for Increasing Treatment Adherence: Systematic Review.Journal of medical Internet research · 2019Pooled it
- Correlation between adherence rates measured by MEMS and self-reported questionnaires: a meta-analysis.Health and quality of life outcomes · 2010Pooled it
- Personalized adherence interventions using medication adherence technologies in polypharmacy management in epilepsy: An interprofessional case report.Epilepsy & behavior reports · 2025Article
- Intake Patterns and Experiences of Patients Using Direct Oral Anticoagulants Measured by Electronic Monitoring in Community Pharmacies.Patient preference and adherence · 2024Article
- Development and acceptance of a new adherence monitoring package to identify non-adherent patients with polypharmacy in primary care: a feasibility study.BMJ open quality · 2023Article
- A New Frontier: Integrating Behavioral and Digital Technology to Promote Health Behavior.The Behavior analyst · 2015Article
- Use of automated medication adherence monitoring in bipolar disorder research: pitfalls, pragmatics, and possibilities.Therapeutic advances in psychopharmacology · 2015Article
- Predicting blood pressure outcomes using single-item physician-administered measures: a retrospective pooled analysis of observational studies in Belgium.The British journal of general practice : the journal of the Royal College of General Practitioners · 2015Observational
- Optimal recall period in assessing the adherence to antihypertensive therapy: a pilot study.International journal of clinical pharmacy · 2011Article
- Concordance of adherence measurement using self-reported adherence questionnaires and medication monitoring devices.PharmacoEconomics · 2010Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the relationship between blood pressure and medication adherence using electronic pillboxes (MEMS).
settingFive general practices in Bristol, UK. SUBJECTS: A total of 239 individuals with a clinical diagnosis of hypertension and being prescribed at least one blood pressure-lowering medication. Participants were asked to use the electronic pillbox as their drug bottle for at least one month.
main outcome measures"Timing adherence" (correct inter-dose intervals) as measured through MEMS and systolic (SBP) and diastolic (DBP) office blood pressure.
resultsMean (+/-SD) timing adherence was 88% (+/-17),>80% in 175 (73%), and less than 50% in 11 (5%) participants. Adherence was monitored for a mean of 33 (+/-6) days. Mean (+/-SD) SBP was 147.9+/-19.1 mmHg and DBP 82.3+/-10.1 mmHg. There was no evidence to suggest that timing adherence was associated with SBP or DBP (overall correlation coefficients -0.01 and -0.02 respectively). According to current guidelines, about one in four of all participants had controlled SBP (only 6% of diabetic patients). DBP was under control in 66% of the individuals.
conclusionsNo relationship between adherence and blood pressure in patients with hypertension recruited from primary care was found. Average timing adherence measured by electronic monitors was high (88%) and blood pressure was controlled in a minority of patients. Our findings suggest that in terms of poor blood pressure control pharmacological non-response to or insufficient intensity of blood pressure-lowering medication might be more important than poor adherence to antihypertensive drug therapy.
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