ArticleParasitology research2008
Gene expression profile of Clonorchis sinensis metacercariae.
Article in Parasitology research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Expression of Transposable Elements throughout theNon-coding RNA · 2024Article
- Molecular and Structural Characterization of the Tegumental 20.6-kDa Protein in Clonorchis sinensis as a Potential Druggable Target.International journal of molecular sciences · 2017Article
- Liver fluke infection and cholangiocarcinoma: a review.Parasitology research · 2017Review
- Molecular characterization of voltage-gated calcium channel β-subunits of Clonorchis sinensis.Parasitology research · 2014Article
- Transcriptome profiling of the fifth-stage larvae of Angiostrongylus cantonensis by next-generation sequencing.Parasitology research · 2013Article
- Quantifying the biomass of parasites to understand their role in aquatic communities.Ecology and evolution · 2013Article
- A deep exploration of the transcriptome and "excretory/secretory" proteome of adult Fascioloides magna.Molecular & cellular proteomics : MCP · 2012Article
- Molecular characterization of an α-N-acetylgalactosaminidase from Clonorchis sinensis.Parasitology research · 2012Article
- Identification and characterization of myophilin-like protein: a life stage and tissue-specific antigen of Clonorchis sinensis.Parasitology research · 2012Article
- Developmental transcriptomic features of the carcinogenic liver fluke, Clonorchis sinensis.PLoS neglected tropical diseases · 2011Article
- A portrait of the transcriptome of the neglected trematode, Fasciola gigantica--biological and biotechnological implications.PLoS neglected tropical diseases · 2011Article
- Unlocking the transcriptomes of two carcinogenic parasites, Clonorchis sinensis and Opisthorchis viverrini.PLoS neglected tropical diseases · 2010Article
- Survey of transcripts expressed by the invasive juvenile stage of the liver fluke Fasciola hepatica.BMC genomics · 2010Article
- Functional genes and proteins of Clonorchis sinensis.The Korean journal of parasitology · 2009Review
- Zoonotic helminth infections with particular emphasis on fasciolosis and other trematodiases.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2009Review
- Reference genes for quantitative analysis on Clonorchis sinensis gene expression by real-time PCR.Parasitology research · 2009Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clonorchis sinensis develop through miracidium, sporocyst, redia, cercaria, and metacercaria stages before becoming egg-laying adult flukes. The authors undertook this analysis of gene expression profiles during developmental stages to increase our understanding of the biology of C. sinensis and of host-parasite relationships. From a C. sinensis metacercariae complementary deoxyribonucleic acid library, 419 expressed sequence tags (ESTs) of average length of 668 bp were collected and assembled into 322 genes containing 70 clusters and 252 singletons. The genes were annotated using BLAST searches and categorized into ten major functional categories. Genes expressed abundantly were those of proteases and metabolic, transcription, and translation housekeeping proteins. Genes expressed higher in C. sinensis metacercariae than in adults coded structural and cytoskeletal proteins, transcription and translation machinery proteins, and energy metabolism-related proteins. This EST information supports the notion that C. sinensis metacercariae in fish hosts have a physiology and metabolism that is quite different from that of its adult form in mammals.
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Registered trials
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